A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Fuad O. Abdullah; Faiq H.S. Hussain; Marco Clericuzio; Alessio Porta; Giovanni Vidari

doi:10.1002/cbdv.201600281

A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Fuad O. Abdullah
, Faiq H.S. Hussain
, Marco Clericuzio
, Alessio Porta
, Giovanni Vidari

Dipartimento di Scienze e Innovazione Tecnologica

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

Lingua originale	Inglese
Numero di articolo	e1600281
Rivista	Chemistry and Biodiversity
Volume	14
Numero di pubblicazione	3
DOI	https://doi.org/10.1002/cbdv.201600281
Stato di pubblicazione	Pubblicato - 1 mar 2017

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title = "A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus N{\'a}b{\v e}lek",

abstract = "Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.",

keywords = "Cytotoxic activities, Dipsacaceae, Iridoid dimers, Kurdish medicinal plant, Pterocephalus nestorianus",

author = "Abdullah, \{Fuad O.\} and Hussain, \{Faiq H.S.\} and Marco Clericuzio and Alessio Porta and Giovanni Vidari",

note = "Publisher Copyright: {\textcopyright} 2017 Wiley-VHCA AG, Zurich, Switzerland",

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doi = "10.1002/cbdv.201600281",

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T1 - A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

AU - Abdullah, Fuad O.

AU - Hussain, Faiq H.S.

AU - Clericuzio, Marco

AU - Porta, Alessio

AU - Vidari, Giovanni

PY - 2017/3/1

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N2 - Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

AB - Accompanied by other rare compounds, a new iridoid dimer, named kurdnestorianoside (1), showing an unprecedented secologanol configuration, has been isolated for the first time from the Kurdish medicinal plant Pterocephalus nestorianus, which is used in Kurdistan for treating oral diseases and inflammation. The structure of 1 was established from 1D- and 2D-NMR spectroscopic data. Kaempferol 3-O-[3,6-di-O-(E)-p-coumaroyl]-β-d-glucopyranoside (7) showed a remarkable antiproliferative activity against several human tumor cell lines.

KW - Cytotoxic activities

KW - Dipsacaceae

KW - Iridoid dimers

KW - Kurdish medicinal plant

KW - Pterocephalus nestorianus

UR - https://www.scopus.com/pages/publications/85014512906

U2 - 10.1002/cbdv.201600281

DO - 10.1002/cbdv.201600281

M3 - Article

SN - 1612-1872

VL - 14

JO - Chemistry and Biodiversity

JF - Chemistry and Biodiversity

IS - 3

M1 - e1600281

ER -

A New Iridoid Dimer and Other Constituents from the Traditional Kurdish Plant Pterocephalus nestorianus Nábělek

Abstract

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