TY - CHAP
T1 - A modular database architecture enabled to comparative sequence analysis
AU - Bonfante, Paola
AU - Cordero, Francesca
AU - Ghignone, Stefano
AU - Ienco, Dino
AU - Lanfranco, Luisa
AU - Leonardi, Giorgio
AU - Meo, Rosa
AU - Montani, Stefania
AU - Roversi, Luca
AU - Visconti, Alessia
PY - 2011
Y1 - 2011
N2 - The beginning of post-genomic era is characterized by a rising numbers of public collected genomes. The evolutionary relationship among these genomes may be caught by means of the comparative analysis of sequences, in order to identify both homologous and non-coding functional elements. In this paper we report on the on-going BIOBITS project. It is focused on studies concerning the bacterial endosymbionts, since they offer an excellent model to investigate important biological events, such as organelle evolution, genome reduction, and transfer of genetic information among host lineages. The BIOBITS goal is two-side: on the one hand, it pursues a logical data representation of genomic and proteomic components. On the other hand, it aims at the development of software modules allowing the user to retrieve and analyze data in a flexible way.
AB - The beginning of post-genomic era is characterized by a rising numbers of public collected genomes. The evolutionary relationship among these genomes may be caught by means of the comparative analysis of sequences, in order to identify both homologous and non-coding functional elements. In this paper we report on the on-going BIOBITS project. It is focused on studies concerning the bacterial endosymbionts, since they offer an excellent model to investigate important biological events, such as organelle evolution, genome reduction, and transfer of genetic information among host lineages. The BIOBITS goal is two-side: on the one hand, it pursues a logical data representation of genomic and proteomic components. On the other hand, it aims at the development of software modules allowing the user to retrieve and analyze data in a flexible way.
UR - http://www.scopus.com/inward/record.url?scp=84856595309&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-23740-9_6
DO - 10.1007/978-3-642-23740-9_6
M3 - Chapter
AN - SCOPUS:84856595309
SN - 9783642237393
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 124
EP - 147
BT - Transactions on Large-Scale Data- and Knowledge-Centered Systems IV
A2 - Hameurlain, Abdelkader
A2 - Kung, Josef
A2 - Wagner, Roland
A2 - Bohm, Christian
A2 - Eder, Johann
A2 - Plant, Claudia
ER -