Abstract
Splitting the amine! The Ugi four-component reaction (Ugi 4CR) relies on the presence of a component with a primary amino group. This protocol has been modified by "splitting" the primary amine into two secondary amines. The resulting variant of the Ugi 4CR proceeds with good to excellent yield and widens the versatility of the original multicomponent reaction by enabling variation of the molecular backbone. (Chemical Equation Presented)
Lingua originale | Inglese |
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pagine (da-a) | 1099-1102 |
Numero di pagine | 4 |
Rivista | Angewandte Chemie - International Edition |
Volume | 45 |
Numero di pubblicazione | 7 |
DOI | |
Stato di pubblicazione | Pubblicato - 6 feb 2006 |