@inproceedings{e4cf6bb96b1447ddb2f10cbb1c21797e,
title = "A MapReduce Based Tool for the Analysis and Discovery of Novel Therapeutic Targets",
abstract = "We present here a novel algorithm based on a MapReduce approach to facilitate the discovery of novel therapeutic targets. The proposed algorithm has been enabled to scan a set biological pathways in order to discover non-trivial (less common) routes. Such routes represent a chain of biochemical interactions among different biological actors. These actors can be represented by quite distant nodes along the devised pathway. Our approach detects nodes that are far from the initial target nodes, also showing the number of times that a given route has been found inside the selected set of biological pathways.",
keywords = "Biochemical Pathway, MAPK1, MapReduce, Python, gene, therapeutic target",
author = "Giuseppe Parasiliti and Marzio Pennisi and Pietro Biondi and Giuseppe Sgroi and Giulia Russo and Christian Napoli and Francesco Pappalardo",
note = "Publisher Copyright: {\textcopyright} 2019 IEEE.; 27th Euromicro International Conference on Parallel, Distributed and Network-Based Processing, PDP 2019 ; Conference date: 13-02-2019 Through 15-02-2019",
year = "2019",
month = mar,
day = "19",
doi = "10.1109/EMPDP.2019.8671609",
language = "English",
series = "Proceedings - 27th Euromicro International Conference on Parallel, Distributed and Network-Based Processing, PDP 2019",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
pages = "323--328",
booktitle = "Proceedings - 27th Euromicro International Conference on Parallel, Distributed and Network-Based Processing, PDP 2019",
address = "United States",
}