A Macromolecular Gd(III) Complex as a pH-Responsive Relaxometric Probe for MRI Applications

S. AIME; Mauro BOTTA; S. GENINATTI CRICH; Giovanni Battista GIOVENZANA; G. PALMISANO; M. SISTI

doi:10.1039/A900499H

A Macromolecular Gd(III) Complex as a pH-Responsive Relaxometric Probe for MRI Applications

S. AIME
, Mauro BOTTA
, S. GENINATTI CRICH
, Giovanni Battista GIOVENZANA
, G. PALMISANO
, M. SISTI

Risultato della ricerca: Contributo su rivista › Articolo in rivista

Abstract

The ability of the paramagnetic macromolecular complex (GdDO3ASQ)₃₀-Orn₁₁₄ to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH₂ groups.

Lingua originale	Inglese
pagine (da-a)	1577-1578
Numero di pagine	2
Rivista	Chemical Communications
DOI	https://doi.org/10.1039/A900499H
Stato di pubblicazione	Pubblicato - 1999

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10.1039/A900499H

http://hdl.handle.net/11579/32731

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@article{ba41b6708fe54bed8f0b455d86a3fd0f,

title = "A Macromolecular Gd(III) Complex as a pH-Responsive Relaxometric Probe for MRI Applications",

abstract = "The ability of the paramagnetic macromolecular complex (GdDO3ASQ)30-Orn114 to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH2 groups.",

author = "S. AIME and Mauro BOTTA and CRICH, \{S. GENINATTI\} and GIOVENZANA, \{Giovanni Battista\} and G. PALMISANO and M. SISTI",

year = "1999",

doi = "10.1039/A900499H",

language = "English",

pages = "1577--1578",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

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T1 - A Macromolecular Gd(III) Complex as a pH-Responsive Relaxometric Probe for MRI Applications

AU - AIME, S.

AU - BOTTA, Mauro

AU - CRICH, S. GENINATTI

AU - GIOVENZANA, Giovanni Battista

AU - PALMISANO, G.

AU - SISTI, M.

PY - 1999

Y1 - 1999

N2 - The ability of the paramagnetic macromolecular complex (GdDO3ASQ)30-Orn114 to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH2 groups.

AB - The ability of the paramagnetic macromolecular complex (GdDO3ASQ)30-Orn114 to enhance the water proton relaxation rate has been found to be a function of pH; this behaviour is related to the structural changes occurring in the polypeptide upon protonation of the side-chain NH2 groups.

UR - https://iris.uniupo.it/handle/11579/32731

U2 - 10.1039/A900499H

DO - 10.1039/A900499H

M3 - Article

SN - 1359-7345

SP - 1577

EP - 1578

JO - Chemical Communications

JF - Chemical Communications

ER -

A Macromolecular Gd(III) Complex as a pH-Responsive Relaxometric Probe for MRI Applications

Abstract

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