A local Renin Angiotensin System in the heart of an African lungfish, Protopterus annectens.

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Abstract

The presence of components of a renin-angiotensin system was investigated in the heart of an African lungfish Protopterus annectens. A renin-like activity is present in heart homogenates. The activity reaches its maximum after 90 min of incubation at 20°C. By a spectrophotometric assay, an angiotensin converting enzyme-like activity was detected. By immunohistochemistry Ile5-Angiotensin II immunoreactive cardiocytes were demonstrated in the atrium and bulbus. Our data indicate that probably a local renin-angiotensin-like system is present in the heart of Protopterus annectens.
Lingua originaleInglese
pagine (da-a)229-233
Numero di pagine5
RivistaCOMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY. PART A, PHYSIOLOGY
Volume110A (3)
DOI
Stato di pubblicazionePubblicato - 1995

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