A degradation product of halobetasol propionate-Characterization and structure

Giancarlo Cravotto; Giovanni B. Giovenzana; Norberto Masciocchi; Giovanni Palmisano; Paolo Volante

doi:10.1016/j.steroids.2007.06.003

A degradation product of halobetasol propionate-Characterization and structure

Giancarlo Cravotto
, Giovanni B. Giovenzana
, Norberto Masciocchi
, Giovanni Palmisano
, Paolo Volante

Dipartimento di Scienze del Farmaco

Risultato della ricerca: Contributo su rivista › Articolo in rivista › peer review

Abstract

Degradation of halobetasol propionate was observed in the presence of bases. A single cyclization product was isolated and fully characterized by MS, NMR and X-ray crystallography.

Lingua originale	Inglese
pagine (da-a)	787-791
Numero di pagine	5
Rivista	Steroids
Volume	72
Numero di pubblicazione	11-12
DOI	https://doi.org/10.1016/j.steroids.2007.06.003
Stato di pubblicazione	Pubblicato - ott 2007

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10.1016/j.steroids.2007.06.003

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@article{f3d7594e6b714a6fa0f268d287dd957d,

title = "A degradation product of halobetasol propionate-Characterization and structure",

abstract = "Degradation of halobetasol propionate was observed in the presence of bases. A single cyclization product was isolated and fully characterized by MS, NMR and X-ray crystallography.",

keywords = "Degradation, Halobetasol propionate, Structure delucidation, Topical corticosteroid",

author = "Giancarlo Cravotto and Giovenzana, \{Giovanni B.\} and Norberto Masciocchi and Giovanni Palmisano and Paolo Volante",

note = "Funding Information: N.M. thanks the Fondazione Cariplo and the Fondazione Provinciale Comasca for partial financial support.",

year = "2007",

month = oct,

doi = "10.1016/j.steroids.2007.06.003",

language = "English",

volume = "72",

pages = "787--791",

journal = "Steroids",

issn = "0039-128X",

publisher = "Elsevier Inc.",

number = "11-12",

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TY - JOUR

T1 - A degradation product of halobetasol propionate-Characterization and structure

AU - Cravotto, Giancarlo

AU - Giovenzana, Giovanni B.

AU - Masciocchi, Norberto

AU - Palmisano, Giovanni

AU - Volante, Paolo

N1 - Funding Information: N.M. thanks the Fondazione Cariplo and the Fondazione Provinciale Comasca for partial financial support.

PY - 2007/10

Y1 - 2007/10

N2 - Degradation of halobetasol propionate was observed in the presence of bases. A single cyclization product was isolated and fully characterized by MS, NMR and X-ray crystallography.

AB - Degradation of halobetasol propionate was observed in the presence of bases. A single cyclization product was isolated and fully characterized by MS, NMR and X-ray crystallography.

KW - Degradation

KW - Halobetasol propionate

KW - Structure delucidation

KW - Topical corticosteroid

UR - https://www.scopus.com/pages/publications/34548297582

U2 - 10.1016/j.steroids.2007.06.003

DO - 10.1016/j.steroids.2007.06.003

M3 - Article

SN - 0039-128X

VL - 72

SP - 787

EP - 791

JO - Steroids

JF - Steroids

IS - 11-12

ER -

A degradation product of halobetasol propionate-Characterization and structure

Abstract

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