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VZV fulminant necrotizing encephalitis with concomitant EBV-related lymphoma and CMV ventriculitis: Report of an AIDS case

  • Manuela Nebuloni
  • , Luca Vago
  • , Renzo Boldorini
  • , Sara Bonetto
  • , Giulio Costanzi

Research output: Contribution to journalArticlepeer-review

Abstract

A case of AIDS with varicella tester virus fulminant necrotizing encephalitis associated with cytomegalovirus ependymitis-subependymitis and a periventricular Epstein-Barr virus-related lymphoma is described. The patient had no herpes tester cutaneous eruptions and died three days after the onset of symptoms, Varicella tester virus and cytomegalovirus antigens were found by immunohistochemistry in the same area around a necrotic periventricular lesion; a periventricular lymphoma, large B cell type, was also observed. In situ hybridization with Epstein-Barr virus-encoded-RNAs probe was positive in about 40% of the neoplastic cells. The association of herpes-related lesions in the same cerebral region should be consistent in AIDS cases with acute neurological symptoms.

Original languageEnglish
Pages (from-to)457-460
Number of pages4
JournalJournal of NeuroVirology
Volume4
Issue number4
DOIs
Publication statusPublished - 1998
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Cytomegalovirus
  • Encephalitis
  • Epstein-Barr virus
  • Human immunodeficiency virus
  • Varicella tester virus

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