UTILITA DEI MODELLI SPERIMENTALI NELLA VALUTAZIONE DI NUOVI FARMACI ANTIEPILETTICI

R. Mutani; R. Cantello; M. Gianelli; P. Naldi; C. Civardi

UTILITA DEI MODELLI SPERIMENTALI NELLA VALUTAZIONE DI NUOVI FARMACI ANTIEPILETTICI

Translated title of the contribution: Assessment of new antiepileptic drugs: Value of experimental models

R. Mutani
, R. Cantello
, M. Gianelli
, P. Naldi
, C. Civardi

Research output: Contribution to journal › Article › peer-review

Abstract

Model tests useful in identifying new antiepileptic drugs are reviewed (screening tests, genetic models and models for partial seizures). Particular emphasis is reserved to the iron model of focal epilepsy and to kindling. These models are relevant to human posttraumatic and temporal lobe epilepsy and are recommended when testing of both the anticonvulsant and the antiepileptogenic properties of potential new drugs is needed.

Translated title of the contribution	Assessment of new antiepileptic drugs: Value of experimental models
Original language	Italian
Pages (from-to)	75-76
Number of pages	2
Journal	Bollettino - Lega Italiana contro l'Epilessia
Issue number	75-76
Publication status	Published - 1991
Externally published	Yes

Cite this

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title = "UTILITA DEI MODELLI SPERIMENTALI NELLA VALUTAZIONE DI NUOVI FARMACI ANTIEPILETTICI",

abstract = "Model tests useful in identifying new antiepileptic drugs are reviewed (screening tests, genetic models and models for partial seizures). Particular emphasis is reserved to the iron model of focal epilepsy and to kindling. These models are relevant to human posttraumatic and temporal lobe epilepsy and are recommended when testing of both the anticonvulsant and the antiepileptogenic properties of potential new drugs is needed.",

author = "R. Mutani and R. Cantello and M. Gianelli and P. Naldi and C. Civardi",

year = "1991",

language = "Italian",

pages = "75--76",

journal = "Bollettino - Lega Italiana contro l'Epilessia",

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publisher = "Lega Italiana contro l'Epilessia",

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TY - JOUR

T1 - UTILITA DEI MODELLI SPERIMENTALI NELLA VALUTAZIONE DI NUOVI FARMACI ANTIEPILETTICI

AU - Mutani, R.

AU - Cantello, R.

AU - Gianelli, M.

AU - Naldi, P.

AU - Civardi, C.

PY - 1991

Y1 - 1991

N2 - Model tests useful in identifying new antiepileptic drugs are reviewed (screening tests, genetic models and models for partial seizures). Particular emphasis is reserved to the iron model of focal epilepsy and to kindling. These models are relevant to human posttraumatic and temporal lobe epilepsy and are recommended when testing of both the anticonvulsant and the antiepileptogenic properties of potential new drugs is needed.

AB - Model tests useful in identifying new antiepileptic drugs are reviewed (screening tests, genetic models and models for partial seizures). Particular emphasis is reserved to the iron model of focal epilepsy and to kindling. These models are relevant to human posttraumatic and temporal lobe epilepsy and are recommended when testing of both the anticonvulsant and the antiepileptogenic properties of potential new drugs is needed.

UR - https://www.scopus.com/pages/publications/0026321228

M3 - Articolo in rivista

AN - SCOPUS:0026321228

SN - 0394-560X

SP - 75

EP - 76

JO - Bollettino - Lega Italiana contro l'Epilessia

JF - Bollettino - Lega Italiana contro l'Epilessia

IS - 75-76

ER -

UTILITA DEI MODELLI SPERIMENTALI NELLA VALUTAZIONE DI NUOVI FARMACI ANTIEPILETTICI

Abstract

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