Triterpenoid Hydroxamates as HIF Prolyl Hydrolase Inhibitors

Keyphrases

• Hydroxamate 100%
• Triterpenoids 100%
• Hydrolase Inhibitors 100%
• Pentacyclic Triterpene Acids 50%
• Chelates 25%
• Inhibitory Activity 25%
• Hypoxic Condition 25%
• NF-B 25%
• Transcription Factor 25%
• Carboxylate 25%
• Neuroprotection 25%
• Hydrolases 25%
• Alkylation 25%
• Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) 25%
• Natural Compounds 25%
• Isoform Selectivity 25%
• Hypoxia-inducible factor-1α (HIF-1α) 25%
• TGR5 25%
• Lead Structure 25%
• Biological Space 25%
• Low-to-moderate 25%
• Betulinic Acid 25%
• Pleiotropic Agents 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Hydroxamic Acid 100%
• Triterpenoid 100%
• Proline Derivative 100%
• Hydrolase Inhibitor 100%
• Natural Product 25%
• Neuroprotection 25%
• Hydrolase 25%
• Transcription Factors 25%
• Carboxylate 25%
• Transcription Factor Nrf2 25%
• Betulinic Acid 25%

Chemistry

• Pentacyclic Triterpenoid 100%
• Triterpenoid 100%
• Hydrolase Inhibitor 100%
• Betulinic Acid 50%
• Carboxylic Acid 50%
• Natural Product 50%
• Transcription Factor 50%
• Transcription Factor Nrf2 50%