The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

TERWILLIGER TC; PARK MS; WALDO GS; J BERENDZEN; HUNG LW; KIM CY; SMITH CV; SACCHETTINI JC; M BELLINZONI; R BOSSI; ROSSI E DE; A MATTEVI; A MILANO; G RICCARDI; Menico RIZZI; ROBERTS MM; COKER AR; G FOSSATI; P MASCAGNI; COATES AR; WOOD SP; GOULDING CW; APOSTOL MI; ANDERSON DH; GILL HS; EISENBERG DS; B TANEJA; S MANDE; E POHL; V LAMZIN; P TUCKER; M WILMANNS; C COLOVOS; KLAUCKE W MEYER; MUNRO AW; MCLEAN KJ; MARSHALL KR; D LEYS; YANG JK; YOON HJ; LEE BI; LEE MG; KWAK JE; HAN BW; LEE JY; BAEK SH; SUH SW; KOMEN MM; ARCUS VL; BAKER EN; LOTT JS; JACOBS W. JR; T ALBER; B. RUPP

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

TERWILLIGER TC
, PARK MS
, WALDO GS
, J BERENDZEN
, HUNG LW
, KIM CY
, SMITH CV
, SACCHETTINI JC
, M BELLINZONI
, R BOSSI
, ROSSI E DE
, A MATTEVI
, A MILANO
, G RICCARDI
, Menico RIZZI
, ROBERTS MM
, COKER AR
, G FOSSATI
, P MASCAGNI
, COATES AR

WOOD SP, GOULDING CW, APOSTOL MI, ANDERSON DH, GILL HS, EISENBERG DS, B TANEJA, S MANDE, E POHL, V LAMZIN, P TUCKER, M WILMANNS, C COLOVOS, KLAUCKE W MEYER, MUNRO AW, MCLEAN KJ, MARSHALL KR, D LEYS, YANG JK, YOON HJ, LEE BI, LEE MG, KWAK JE, HAN BW, LEE JY, BAEK SH, SUH SW, KOMEN MM, ARCUS VL, BAKER EN, LOTT JS, JACOBS W. JR, T ALBER, B. RUPP

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

Original language	English
Pages (from-to)	223-249
Number of pages	27
Journal	Tuberculosis
Volume	83
Publication status	Published - 2003

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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http://hdl.handle.net/11579/18294

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TC, TERWILLIGER., MS, PARK., GS, WALDO., BERENDZEN, J., LW, HUNG., CY, KIM., CV, SMITH., JC, SACCHETTINI., BELLINZONI, M., BOSSI, R., DE, ROSSI. E., MATTEVI, A., MILANO, A., RICCARDI, G., RIZZI, M., MM, ROBERTS., AR, COKER., FOSSATI, G., MASCAGNI, P., ... RUPP, B. (2003). The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis, 83, 223-249. http://hdl.handle.net/11579/18294

@article{73e125f4b4904401a1d21445522693c7,

title = "The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology",

abstract = "The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.",

author = "TERWILLIGER TC and PARK MS and WALDO GS and J BERENDZEN and HUNG LW and KIM CY and SMITH CV and SACCHETTINI JC and M BELLINZONI and R BOSSI and DE, \{ROSSI E\} and A MATTEVI and A MILANO and G RICCARDI and Menico RIZZI and ROBERTS MM and COKER AR and G FOSSATI and P MASCAGNI and COATES AR and WOOD SP and GOULDING CW and APOSTOL MI and ANDERSON DH and GILL HS and EISENBERG DS and B TANEJA and S MANDE and E POHL and V LAMZIN and P TUCKER and M WILMANNS and C COLOVOS and MEYER, \{KLAUCKE W\} and MUNRO AW and MCLEAN KJ and MARSHALL KR and D LEYS and YANG JK and YOON HJ and LEE BI and LEE MG and KWAK JE and HAN BW and LEE JY and BAEK SH and SUH SW and KOMEN MM and ARCUS VL and BAKER EN and LOTT JS and JR, \{JACOBS W.\} and T ALBER and B. RUPP",

note = "Funding Information: Work from the laboratory of Se Won Suh was supported by the Korea Ministry of Science and Technology (NRL-2001, grant no. M1-0104000132-01J000006210). Work from the laboratory of University of Pavia was supported by the Italian Ministry of University and Scientific and Technological Research (MURST, grant COFIN-1998, COFIN-2002) and by the European Union research project Quality of Life and Management of Living Resources (Contract No. QLK2-2000-01761). Work from many of the laboratories was supported by the NIH. The UCLA authors wish to acknowledge Mari Gingery, Duilio Cascio, Michael Sawaya and Cameron Mura for useful suggestions and discussion. The UCLA work has been supported by grants from the Department of Energy and the National Institutes of Health. The coordinates for Rv1886c, Rv2220, Rv1926c and Rv2878c have been deposited in the Protein Data Bank with the accession numbers 1FOP , 1HTO, 1LM1 and 1LU4, respectively. The SGHMS authors wish to thank Jon Cooper, Darren Thompson, Gerard Kleywegt and Peter Tormay for their help and advice, the Raymond Burton Medical Trust for a grant to A.R.M.C. and the Wellcome Trust for a grant to S.P.W. We would like to thank David Christie for originally suggesting this area of study at Auckland, Kerry Loomes for help and advice with lipase assays, the Auckland Medical Research Foundation for a project grant to V.A. and J.S.L, and the New Economy Research Fund and the Marsden Fund for project grants to E.N.B. ",

year = "2003",

language = "English",

volume = "83",

pages = "223--249",

journal = "Tuberculosis",

issn = "1472-9792",

publisher = "Churchill Livingstone",

}

TC, TERWILLIGER, MS, PARK, GS, WALDO, BERENDZEN, J, LW, HUNG, CY, KIM, CV, SMITH, JC, SACCHETTINI, BELLINZONI, M, BOSSI, R, DE, ROSSIE, MATTEVI, A, MILANO, A, RICCARDI, G, RIZZI, M, MM, ROBERTS, AR, COKER, FOSSATI, G, MASCAGNI, P, AR, COATES, SP, WOOD, CW, GOULDING, MI, APOSTOL, DH, ANDERSON, HS, GILL, DS, EISENBERG, TANEJA, B, MANDE, S, POHL, E, LAMZIN, V, TUCKER, P, WILMANNS, M, COLOVOS, C, MEYER, KLAUCKEW, AW, MUNRO, KJ, MCLEAN, KR, MARSHALL, LEYS, D, JK, YANG, HJ, YOON, BI, LEE, MG, LEE, JE, KWAK, BW, HAN, JY, LEE, SH, BAEK, SW, SUH, MM, KOMEN, VL, ARCUS, EN, BAKER, JS, LOTT, JR, JACOBSW, ALBER, T & RUPP, B 2003, 'The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology', Tuberculosis, vol. 83, pp. 223-249. <http://hdl.handle.net/11579/18294>

TY - JOUR

T1 - The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

AU - TC, TERWILLIGER

AU - MS, PARK

AU - GS, WALDO

AU - BERENDZEN, J

AU - LW, HUNG

AU - CY, KIM

AU - CV, SMITH

AU - JC, SACCHETTINI

AU - BELLINZONI, M

AU - BOSSI, R

AU - DE, ROSSI E

AU - MATTEVI, A

AU - MILANO, A

AU - RICCARDI, G

AU - RIZZI, Menico

AU - MM, ROBERTS

AU - AR, COKER

AU - FOSSATI, G

AU - MASCAGNI, P

AU - AR, COATES

AU - SP, WOOD

AU - CW, GOULDING

AU - MI, APOSTOL

AU - DH, ANDERSON

AU - HS, GILL

AU - DS, EISENBERG

AU - TANEJA, B

AU - MANDE, S

AU - POHL, E

AU - LAMZIN, V

AU - TUCKER, P

AU - WILMANNS, M

AU - COLOVOS, C

AU - MEYER, KLAUCKE W

AU - AW, MUNRO

AU - KJ, MCLEAN

AU - KR, MARSHALL

AU - LEYS, D

AU - JK, YANG

AU - HJ, YOON

AU - BI, LEE

AU - MG, LEE

AU - JE, KWAK

AU - BW, HAN

AU - JY, LEE

AU - SH, BAEK

AU - SW, SUH

AU - MM, KOMEN

AU - VL, ARCUS

AU - EN, BAKER

AU - JS, LOTT

AU - JR, JACOBS W.

AU - ALBER, T

AU - RUPP, B.

N1 - Funding Information: Work from the laboratory of Se Won Suh was supported by the Korea Ministry of Science and Technology (NRL-2001, grant no. M1-0104000132-01J000006210). Work from the laboratory of University of Pavia was supported by the Italian Ministry of University and Scientific and Technological Research (MURST, grant COFIN-1998, COFIN-2002) and by the European Union research project Quality of Life and Management of Living Resources (Contract No. QLK2-2000-01761). Work from many of the laboratories was supported by the NIH. The UCLA authors wish to acknowledge Mari Gingery, Duilio Cascio, Michael Sawaya and Cameron Mura for useful suggestions and discussion. The UCLA work has been supported by grants from the Department of Energy and the National Institutes of Health. The coordinates for Rv1886c, Rv2220, Rv1926c and Rv2878c have been deposited in the Protein Data Bank with the accession numbers 1FOP , 1HTO, 1LM1 and 1LU4, respectively. The SGHMS authors wish to thank Jon Cooper, Darren Thompson, Gerard Kleywegt and Peter Tormay for their help and advice, the Raymond Burton Medical Trust for a grant to A.R.M.C. and the Wellcome Trust for a grant to S.P.W. We would like to thank David Christie for originally suggesting this area of study at Auckland, Kerry Loomes for help and advice with lipase assays, the Auckland Medical Research Foundation for a project grant to V.A. and J.S.L, and the New Economy Research Fund and the Marsden Fund for project grants to E.N.B.

PY - 2003

Y1 - 2003

N2 - The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

AB - The TB Structural Genomics Consortium is an organization devoted to encouraging, coordinating, and facilitating the determination and analysis of structures of proteins from Mycobacterium tuberculosis. The Consortium members hope to work together with other M. tuberculosis researchers to identify M. tuberculosis proteins for which structural information could provide important biological information, to analyze and interpret structures of M. tuberculosis proteins, and to work collaboratively to test ideas about M. tuberculosis protein function that are suggested by structure or related to structural information. This review describes the TB Structural Genomics Consortium and some of the proteins for which the Consortium is in the progress of determining three-dimensional structures.

UR - https://iris.uniupo.it/handle/11579/18294

M3 - Article

SN - 1472-9792

VL - 83

SP - 223

EP - 249

JO - Tuberculosis

JF - Tuberculosis

ER -

The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology

Abstract

UN SDGs

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