Abstract
The aim of this study was to evaluate the plasma absorption of i.m. administered exogenous urinary follicle stimulating hormone (FSH) in relation to body fatness, leanness and cell mass. Body composition was measured by means of bioelectrical impedance. An immunoradiometric assay was used to assess the concentration of exogenous FSH in blood in patients with a pharmacologically induced hypogonadotrophism who were undergoing ovulation induction for assisted reproduction. No correlation was found between body composition and the hormone concentration in blood. According to our results, the different requirements of gonadotrophin administration typically observed in patients of different weights are probably not related to different absorption and distribution of the drug.
| Original language | English |
|---|---|
| Pages (from-to) | 1001-1004 |
| Number of pages | 4 |
| Journal | Human Reproduction |
| Volume | 8 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 1993 |
| Externally published | Yes |
Keywords
- Body composition
- Menotrophins
- Ovulation induction
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