The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Federica Compostella; Luigi Panza; Fiamma Ronchetti

doi:10.1016/j.crci.2011.09.011

The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Federica Compostella
, Luigi Panza
, Fiamma Ronchetti

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Sulfatide is one of the most relevant endogenous acidic glycolipids found in mammal membranes, ubiquitously present in various tissues. The review will briefly introduce the physiopathological role of sulfatide, then focusing mainly on synthetic aspects related to the preparation of this molecule and of analogues thereof, as tools to better understand its biological role, its involvement in pathogenesis and to stimulate the research towards development of new derivatives for biomedical applications.

Original language	English
Pages (from-to)	37-45
Number of pages	9
Journal	Comptes Rendus Chimie
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.crci.2011.09.011
Publication status	Published - Jan 2012

Keywords

Carbohydrates
Galactosylceramide
Glycosphingolipids
Glycosylation

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10.1016/j.crci.2011.09.011

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abstract = "Sulfatide is one of the most relevant endogenous acidic glycolipids found in mammal membranes, ubiquitously present in various tissues. The review will briefly introduce the physiopathological role of sulfatide, then focusing mainly on synthetic aspects related to the preparation of this molecule and of analogues thereof, as tools to better understand its biological role, its involvement in pathogenesis and to stimulate the research towards development of new derivatives for biomedical applications.",

keywords = "Carbohydrates, Galactosylceramide, Glycosphingolipids, Glycosylation",

author = "Federica Compostella and Luigi Panza and Fiamma Ronchetti",

note = "Funding Information: The authors gratefully thank the University of Milan and the University of Piemonte Orientale for financial support.",

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AU - Panza, Luigi

AU - Ronchetti, Fiamma

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PY - 2012/1

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AB - Sulfatide is one of the most relevant endogenous acidic glycolipids found in mammal membranes, ubiquitously present in various tissues. The review will briefly introduce the physiopathological role of sulfatide, then focusing mainly on synthetic aspects related to the preparation of this molecule and of analogues thereof, as tools to better understand its biological role, its involvement in pathogenesis and to stimulate the research towards development of new derivatives for biomedical applications.

KW - Carbohydrates

KW - Galactosylceramide

KW - Glycosphingolipids

KW - Glycosylation

UR - https://www.scopus.com/pages/publications/84855694337

U2 - 10.1016/j.crci.2011.09.011

DO - 10.1016/j.crci.2011.09.011

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ER -

The mammalian sulfated glycolipid sulfatide: Synthesis and biological implications

Abstract

Keywords

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