The human Y chromosome shows a low level of DNA polymorphism

P. MALASPINA; F. PERSICHETTI; A. NOVELLETTO; C. IODICE; L. TERRENATO; J. WOLFE; M. FERRARO; G. PRANTERA

doi:10.1111/j.1469-1809.1990.tb00385.x

The human Y chromosome shows a low level of DNA polymorphism

P. MALASPINA
, F. PERSICHETTI
, A. NOVELLETTO
, C. IODICE
, L. TERRENATO
, J. WOLFE
, M. FERRARO
, G. PRANTERA

Research output: Contribution to journal › Article › peer-review

Abstract

Six new Y‐specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

Original language	English
Pages (from-to)	297-305
Number of pages	9
Journal	Annals of Human Genetics
Volume	54
Issue number	4
DOIs	https://doi.org/10.1111/j.1469-1809.1990.tb00385.x
Publication status	Published - Oct 1990
Externally published	Yes

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10.1111/j.1469-1809.1990.tb00385.x

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title = "The human Y chromosome shows a low level of DNA polymorphism",

abstract = "Six new Y‐specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.",

author = "P. MALASPINA and F. PERSICHETTI and A. NOVELLETTO and C. IODICE and L. TERRENATO and J. WOLFE and M. FERRARO and G. PRANTERA",

year = "1990",

month = oct,

doi = "10.1111/j.1469-1809.1990.tb00385.x",

language = "English",

volume = "54",

pages = "297--305",

journal = "Annals of Human Genetics",

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T1 - The human Y chromosome shows a low level of DNA polymorphism

AU - MALASPINA, P.

AU - PERSICHETTI, F.

AU - NOVELLETTO, A.

AU - IODICE, C.

AU - TERRENATO, L.

AU - WOLFE, J.

AU - FERRARO, M.

AU - PRANTERA, G.

PY - 1990/10

Y1 - 1990/10

N2 - Six new Y‐specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

AB - Six new Y‐specific probes have been isolated and are reported. Along with another six already described they have been used in a systematic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

UR - https://www.scopus.com/pages/publications/0025223207

U2 - 10.1111/j.1469-1809.1990.tb00385.x

DO - 10.1111/j.1469-1809.1990.tb00385.x

M3 - Article

SN - 0003-4800

VL - 54

SP - 297

EP - 305

JO - Annals of Human Genetics

JF - Annals of Human Genetics

IS - 4

ER -

The human Y chromosome shows a low level of DNA polymorphism

Abstract

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