The furoxan system: Design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasolidating activities

Keyphrases

• Furoxan 100%
• Cyclooxygenase-2 100%
• System Design 100%
• Nitric Oxide Donors 100%
• Diphenyl 66%
• Platelets 33%
• Release Properties 33%
• Nitric Oxide 33%
• Furazan 33%
• Cardiotoxicity 33%
• Nitric Oxide Release 33%
• Inhibiting Activity 33%
• Phenyl Group 33%
• Furoxan Derivatives 33%
• Molecular Docking Studies 33%
• Selective COX-2 33%
• 1,2,5-oxadiazole 33%
• 1,2,5-Oxadiazole 2-oxides 33%
• Selective COX-2 Inhibitors 33%

Pharmacology, Toxicology and Pharmaceutical Science

• Nitric Oxide 100%
• Biphenyl 100%
• Nitric Oxide Donor 100%
• Oxadiazole Derivative 100%
• Cardiotoxicity 50%
• COX-2 Inhibitor 50%
• Phenyl Group 50%

Chemistry

• Nitric Oxide 100%
• 1,2,5-oxadiazole 100%
• Nitric Oxide Donor 100%
• Oxide(2-) 50%
• Phenyl Group 50%