Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening

Fikriye Ozgencil; Selen Ozge Almamis; Huseyin Cimen; Alberto MASSAROTTI; Gokcen Eren

doi:10.1016/j.bmc.2026.118754

Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening

Fikriye Ozgencil
, Selen Ozge Almamis
, Huseyin Cimen
, Alberto MASSAROTTI
, Gokcen Eren

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Bioorganic and Medicinal Chemistry
Volume	141
DOIs	https://doi.org/10.1016/j.bmc.2026.118754
Publication status	Published - 2026

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10.1016/j.bmc.2026.118754

https://hdl.handle.net/11579/235402

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title = "Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening",

author = "Fikriye Ozgencil and Almamis, \{Selen Ozge\} and Huseyin Cimen and Alberto MASSAROTTI and Gokcen Eren",

year = "2026",

doi = "10.1016/j.bmc.2026.118754",

language = "English",

volume = "141",

journal = "Bioorganic and Medicinal Chemistry",

issn = "0968-0896",

publisher = "Elsevier Ltd.",

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TY - JOUR

T1 - Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening

AU - Ozgencil, Fikriye

AU - Almamis, Selen Ozge

AU - Cimen, Huseyin

AU - MASSAROTTI, Alberto

AU - Eren, Gokcen

PY - 2026

Y1 - 2026

UR - https://iris.uniupo.it/handle/11579/235402

U2 - 10.1016/j.bmc.2026.118754

DO - 10.1016/j.bmc.2026.118754

M3 - Article

SN - 0968-0896

VL - 141

JO - Bioorganic and Medicinal Chemistry

JF - Bioorganic and Medicinal Chemistry

ER -

Targeting the NAD+ salvage pathway: Identification of bifunctional NAMPT inhibitors and SIRT1 activators through pharmacophore-based virtual screening

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