Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Silvia Ronchi; Davide Prosperi; Federica Compostella; Luigi Panza

doi:10.1055/s-2004-822897

Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Silvia Ronchi, Davide Prosperi, Federica Compostella, Luigi Panza

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

Original language	English
Pages (from-to)	1007-1010
Number of pages	4
Journal	Synlett
Issue number	6
DOIs	https://doi.org/10.1055/s-2004-822897
Publication status	Published - 6 May 2004

Keywords

Amino acids
Boron
Carborane cluster
Glycosides
Medicinal chemistry

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title = "Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy",

abstract = "Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.",

keywords = "Amino acids, Boron, Carborane cluster, Glycosides, Medicinal chemistry",

author = "Silvia Ronchi and Davide Prosperi and Federica Compostella and Luigi Panza",

year = "2004",

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doi = "10.1055/s-2004-822897",

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AU - Ronchi, Silvia

AU - Prosperi, Davide

AU - Compostella, Federica

AU - Panza, Luigi

PY - 2004/5/6

Y1 - 2004/5/6

N2 - Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

AB - Cyanuric chloride has been used as a scaffold for the synthesis of potential agents for BNCT containing a carborane cluster, a sugar moiety as hydrophilic arm and an amino acid for the conjugation with bioactive molecules; this approach is, in principle, particularly suitable for a combinatorial approach.

KW - Amino acids

KW - Boron

KW - Carborane cluster

KW - Glycosides

KW - Medicinal chemistry

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U2 - 10.1055/s-2004-822897

DO - 10.1055/s-2004-822897

M3 - Article

SN - 0936-5214

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JO - Synlett

JF - Synlett

IS - 6

ER -

Synthesis of novel carborane-hybrids based on a triazine scaffold for boron neutron capture therapy

Abstract

Keywords

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