Study on the photostability of octyl-p-methoxy cinnamate in SLN

M. E. CARLOTTI; S. SAPINO; D. VIONE; E. PELIZZETTI; E. UGAZIO; Silvia MOREL

Study on the photostability of octyl-p-methoxy cinnamate in SLN

M. E. CARLOTTI
, S. SAPINO
, D. VIONE
, E. PELIZZETTI
, E. UGAZIO
, Silvia MOREL

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article

Abstract

The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.

Original language	English
Pages (from-to)	809-816
Journal	Journal of Dispersion Science and Technology
Volume	26
Publication status	Published - 2005

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http://hdl.handle.net/11579/20236

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title = "Study on the photostability of octyl-p-methoxy cinnamate in SLN",

abstract = "The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.",

author = "CARLOTTI, \{M. E.\} and S. SAPINO and D. VIONE and E. PELIZZETTI and E. UGAZIO and Silvia MOREL",

year = "2005",

language = "English",

volume = "26",

pages = "809--816",

journal = "Journal of Dispersion Science and Technology",

issn = "0193-2691",

publisher = "Taylor and Francis Ltd.",

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TY - JOUR

T1 - Study on the photostability of octyl-p-methoxy cinnamate in SLN

AU - CARLOTTI, M. E.

AU - SAPINO, S.

AU - VIONE, D.

AU - PELIZZETTI, E.

AU - UGAZIO, E.

AU - MOREL, Silvia

PY - 2005

Y1 - 2005

N2 - The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.

AB - The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.

UR - https://iris.uniupo.it/handle/11579/20236

M3 - Article

SN - 0193-2691

VL - 26

SP - 809

EP - 816

JO - Journal of Dispersion Science and Technology

JF - Journal of Dispersion Science and Technology

ER -

Study on the photostability of octyl-p-methoxy cinnamate in SLN

Abstract

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