Study on the photostability of octyl-p-methoxy cinnamate in SLN

M. Eugenia Carlotti, S. Sapino, D. Vione, E. Pelizzetti, E. Ugazio, S. Morel

Research output: Contribution to journalArticlepeer-review

Abstract

The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.

Original languageEnglish
Pages (from-to)809-816
Number of pages8
JournalJournal of Dispersion Science and Technology
Volume26
Issue number6
DOIs
Publication statusPublished - 2005

Keywords

  • Nonionic surfactant
  • Photo protection
  • Solid lipid nanoparticles (SLNs)
  • Sunscreen

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