Abstract
The aim of this study was to prepare solid lipid nanoparticles (SLNs) of octyl-p-methoxycinnamate (OMC) to improve the photostability of this UV adsorber. It was found that the rate of photodegradation is significantly dependent upon the initial concentration of the active substance and could be halved in SLN form. When different concentration of nonionic surfactant solutions were compared, it was found that OMC photodegraded more quickly from a medium containing fewer surfactant micelles. Photodegradation rate of OMC was investigated spectrophotometrically while nanoparticles were characterized by particle size examination, zeta potential determination, and thermal analysis.
Original language | English |
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Pages (from-to) | 809-816 |
Number of pages | 8 |
Journal | Journal of Dispersion Science and Technology |
Volume | 26 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2005 |
Keywords
- Nonionic surfactant
- Photo protection
- Solid lipid nanoparticles (SLNs)
- Sunscreen