Abstract
In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.
Original language | English |
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Pages (from-to) | 1036-1046 |
Number of pages | 11 |
Journal | Journal of Biomedical Materials Research - Part A |
Volume | 101 A |
Issue number | 4 |
DOIs | |
Publication status | Published - Apr 2013 |
Keywords
- Bioactivity
- Blend
- Fatty acid
- Gelatin
- Immunocytochemistry
- Polyurethane