Study on the interaction between gelatin and polyurethanes derived from fatty acids

R. J. González-Paz, G. Lligadas, J. C. Ronda, M. Galià, A. M. Ferreira, F. Boccafoschi, G. Ciardelli, V. Cádiz

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, gelatin was blended to proprietary noncytotoxic polyurethanes (PU) derived from vegetable oils with different weight ratios, as material for the preparation of novel biomedical products. The PU/gelatin blends were characterized for their morphology through scanning electron microscopy. Mechanical and thermal properties, chemical interactions between components, degradation behavior, surface properties, cell adhesion, and bioactivity were investigated as a function of the protein content. Higher blend miscibility was observed for the amorphous PUs, derived from oleic acid. Properties of PU/gelatin films were strongly influenced by the concentration of gelatin in the films. Gelatin enhanced the hydrophilicity, bioactivity, and cell adhesion of PUs.

Original languageEnglish
Pages (from-to)1036-1046
Number of pages11
JournalJournal of Biomedical Materials Research - Part A
Volume101 A
Issue number4
DOIs
Publication statusPublished - Apr 2013

Keywords

  • Bioactivity
  • Blend
  • Fatty acid
  • Gelatin
  • Immunocytochemistry
  • Polyurethane

Fingerprint

Dive into the research topics of 'Study on the interaction between gelatin and polyurethanes derived from fatty acids'. Together they form a unique fingerprint.

Cite this