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Stereoselective synthesis of trans-β-lactams by palladium-catalysed carbonylation of vinyl aziridines

  • Francesco Fontana
  • , Gian Cesare Tron
  • , Nekane Barbero
  • , Serena Ferrini
  • , Stephen P. Thomas
  • , Varinder K. Aggarwal

Research output: Contribution to journalArticlepeer-review

Abstract

The palladium-catalysed carbonylation of vinyl aziridines can give either the trans- or cis-β-lactam preferentially or even the δ-lactam simply by adjusting the reaction parameters ([Pd], [CO], temperature).

Original languageEnglish
Pages (from-to)267-269
Number of pages3
JournalChemical Communications
Volume46
Issue number2
DOIs
Publication statusPublished - 2010
Externally publishedYes

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