Rose Bengal incorporated in mesostructured silica nanoparticles: structural characterization, theoretical modeling and singlet oxygen delivery

B. Martins Estevão, F. Cucinotta, N. Hioka, M. Cossi, M. Argeri, G. Paul, L. Marchese, E. Gianotti

Research output: Contribution to journalArticlepeer-review

Abstract

Rose Bengal (RB), a xanthene dye, incorporated into mesostructured silica nanoparticles (MSNs) exhibits efficient singlet oxygen (1O2) generation when illuminated with 540 nm green light which is particularly promising for PDT applications. Several systems with different RB loadings were synthesized and fully characterized by means of spectroscopic techniques in combination with a computational study, to optimize the amount of RB in order to avoid the formation of aggregates that is detrimental for a high 1O2 delivery.

Original languageEnglish
Pages (from-to)26804-26812
Number of pages9
JournalPhysical Chemistry Chemical Physics
Volume17
Issue number40
DOIs
Publication statusPublished - 2015

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