Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Berardino De Bari; Raphael Jumeau; Letizia Deantonio; Salim Adib; Sarah Godin; Michele Zeverino; Raphael Moeckli; Jean Bourhis; John O. Prior; Mahmut Ozsahin

doi:10.5301/tj.5000523

Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Berardino De Bari
, Raphael Jumeau
, Letizia Deantonio
, Salim Adib
, Sarah Godin
, Michele Zeverino
, Raphael Moeckli
, Jean Bourhis
, John O. Prior
, Mahmut Ozsahin

Research output: Contribution to journal › Article › peer-review

Abstract

We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

Original language	English
Pages (from-to)	e21-e24
Journal	Tumori
Volume	102
Issue number	5
DOIs	https://doi.org/10.5301/tj.5000523
Publication status	Published - 1 Sept 2016
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Hepatocellular carcinoma
Liver cancer
Stereotactic body radiation therapy (SBRT)
Tc-mebrofenin hepatobiliary scintigraphy (HBS)
Toxicity

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10.5301/tj.5000523

Cite this

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title = "Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer",

abstract = "We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.",

keywords = "Hepatocellular carcinoma, Liver cancer, Stereotactic body radiation therapy (SBRT), Tc-mebrofenin hepatobiliary scintigraphy (HBS), Toxicity",

author = "\{De Bari\}, Berardino and Raphael Jumeau and Letizia Deantonio and Salim Adib and Sarah Godin and Michele Zeverino and Raphael Moeckli and Jean Bourhis and Prior, \{John O.\} and Mahmut Ozsahin",

year = "2016",

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doi = "10.5301/tj.5000523",

language = "English",

volume = "102",

pages = "e21--e24",

journal = "Tumori",

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TY - JOUR

T1 - Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

AU - De Bari, Berardino

AU - Jumeau, Raphael

AU - Deantonio, Letizia

AU - Adib, Salim

AU - Godin, Sarah

AU - Zeverino, Michele

AU - Moeckli, Raphael

AU - Bourhis, Jean

AU - Prior, John O.

AU - Ozsahin, Mahmut

PY - 2016/9/1

Y1 - 2016/9/1

N2 - We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

AB - We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

KW - Hepatocellular carcinoma

KW - Liver cancer

KW - Stereotactic body radiation therapy (SBRT)

KW - Tc-mebrofenin hepatobiliary scintigraphy (HBS)

KW - Toxicity

UR - https://www.scopus.com/pages/publications/84995592114

U2 - 10.5301/tj.5000523

DO - 10.5301/tj.5000523

M3 - Article

SN - 0300-8916

VL - 102

SP - e21-e24

JO - Tumori

JF - Tumori

IS - 5

ER -

Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Abstract

UN SDGs

Keywords

Access to Document

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