Role of functional imaging in treatment plan optimization of stereotactic body radiation therapy for liver cancer

Berardino De Bari, Raphael Jumeau, Letizia Deantonio, Salim Adib, Sarah Godin, Michele Zeverino, Raphael Moeckli, Jean Bourhis, John O. Prior, Mahmut Ozsahin

Research output: Contribution to journalArticlepeer-review

Abstract

We report the first known instance of the clinical use of 99mTc-mebrofenin hepatobiliary scintigraphy (HBS) for the optimization of radiotherapy treatment planning and for the follow-up of acute toxicity in a patient undergoing stereotactic body radiation therapy for hepatocellular carcinoma. In our experience, HBS allowed the identification and the sparing of more functioning liver areas, thus potentially reducing the risk of radiation-induced liver toxicity.

Original languageEnglish
Pages (from-to)e21-e24
JournalTumori
Volume102
Issue number5
DOIs
Publication statusPublished - 1 Sept 2016
Externally publishedYes

Keywords

  • Hepatocellular carcinoma
  • Liver cancer
  • Stereotactic body radiation therapy (SBRT)
  • Tc-mebrofenin hepatobiliary scintigraphy (HBS)
  • Toxicity

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