Relaxivity Modulation of Gd-HPDO3A-like Complexes by Introducing Polar and Protic Peripheral Groups

Keyphrases

• Functional Groups 100%
• Relaxivity 100%
• Gd-HPDO3A 100%
• Peripheral Group 100%
• Protic 100%
• Contrast Agent 66%
• 1H nuclear Magnetic Resonance (1H NMR) 33%
• Gd(III) 33%
• DO3A 33%
• 1,4,7,10-tetraazacyclododecane 33%
• Water Molecule 33%
• Hydrogen Bonds (H-bonds) 33%
• Hydroxyl Group 33%
• Amides 33%
• High Relaxivity 33%
• Magnetic Resonance Imaging Contrast Agents 33%
• Diols 33%
• Phosphonates 33%
• Second-sphere 33%
• Hydroxypropyl 33%
• Prototropic 33%
• Labile Protons 33%
• Injected Dose 33%

Chemistry

• Contrast Medium 100%
• 1H NMR Spectroscopy 50%
• 1,4,7,10-tetraazacyclododecane 50%
• Triacetic Acid 50%
• Hydroxyl Group 50%
• Nuclear Magnetic Resonance Imaging Agent 50%
• Phosphonate 50%
• Amide 50%
• Diol 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Functional Groups 100%
• Contrast Medium 66%
• Carboxamide 33%
• Phosphonate 33%
• Hydroxyl Group 33%
• Nuclear Magnetic Resonance Imaging Agent 33%