Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

Pierfrancesco Franco; Francesca Arcadipane; Paolo Strignano; Rosella Spadi; Elisabetta Trino; Stefania Martini; Giuseppe Carlo Iorio; Maria Antonietta Satolli; Mario Airoldi; Renato Romagnoli; Michele Camandona; Umberto Ricardi

doi:10.1007/s12032-017-0898-1

Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

Pierfrancesco Franco
, Francesca Arcadipane
, Paolo Strignano
, Rosella Spadi
, Elisabetta Trino
, Stefania Martini
, Giuseppe Carlo Iorio
, Maria Antonietta Satolli
, Mario Airoldi
, Renato Romagnoli
, Michele Camandona
, Umberto Ricardi

Research output: Contribution to journal › Review article › peer-review

Abstract

Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.

Original language	English
Article number	40
Journal	Medical Oncology
Volume	34
Issue number	3
DOIs	https://doi.org/10.1007/s12032-017-0898-1
Publication status	Published - 1 Mar 2017
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Adenocarcinoma
Gastro-oesophageal junction
Neoadjuvant chemotherapy
Oesophageal cancer
Pre-operative chemo-radiation
Radiotherapy

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10.1007/s12032-017-0898-1

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Franco, P., Arcadipane, F., Strignano, P., Spadi, R., Trino, E., Martini, S., Iorio, G. C., Satolli, M. A., Airoldi, M., Romagnoli, R., Camandona, M., & Ricardi, U. (2017). Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials. Medical Oncology, 34(3), Article 40. https://doi.org/10.1007/s12032-017-0898-1

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title = "Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials",

abstract = "Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.",

keywords = "Adenocarcinoma, Gastro-oesophageal junction, Neoadjuvant chemotherapy, Oesophageal cancer, Pre-operative chemo-radiation, Radiotherapy",

author = "Pierfrancesco Franco and Francesca Arcadipane and Paolo Strignano and Rosella Spadi and Elisabetta Trino and Stefania Martini and Iorio, \{Giuseppe Carlo\} and Satolli, \{Maria Antonietta\} and Mario Airoldi and Renato Romagnoli and Michele Camandona and Umberto Ricardi",

note = "Publisher Copyright: {\textcopyright} 2017, Springer Science+Business Media New York.",

year = "2017",

month = mar,

day = "1",

doi = "10.1007/s12032-017-0898-1",

language = "English",

volume = "34",

journal = "Medical Oncology",

issn = "1357-0560",

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Franco, P, Arcadipane, F, Strignano, P, Spadi, R, Trino, E, Martini, S, Iorio, GC, Satolli, MA, Airoldi, M, Romagnoli, R, Camandona, M & Ricardi, U 2017, 'Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials', Medical Oncology, vol. 34, no. 3, 40. https://doi.org/10.1007/s12032-017-0898-1

TY - JOUR

T1 - Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction

T2 - a review of the current evidence from randomized trials

AU - Franco, Pierfrancesco

AU - Arcadipane, Francesca

AU - Strignano, Paolo

AU - Spadi, Rosella

AU - Trino, Elisabetta

AU - Martini, Stefania

AU - Iorio, Giuseppe Carlo

AU - Satolli, Maria Antonietta

AU - Airoldi, Mario

AU - Romagnoli, Renato

AU - Camandona, Michele

AU - Ricardi, Umberto

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.

AB - Adenocarcinomas of the lower oesophagus and gastro-oesophageal junction are a complex clinico-pathological setting. Multimodality therapy is considered mandatory in most disease presentations. Nevertheless, the most appropriate treatment package has yet to be established. We herein summarize the evidence derived from randomized phase III trials on pre-operative treatments in this oncological scenario.

KW - Adenocarcinoma

KW - Gastro-oesophageal junction

KW - Neoadjuvant chemotherapy

KW - Oesophageal cancer

KW - Pre-operative chemo-radiation

KW - Radiotherapy

U2 - 10.1007/s12032-017-0898-1

DO - 10.1007/s12032-017-0898-1

M3 - Review article

SN - 1357-0560

VL - 34

JO - Medical Oncology

JF - Medical Oncology

IS - 3

M1 - 40

ER -

Pre-operative treatments for adenocarcinoma of the lower oesophagus and gastro-oesophageal junction: a review of the current evidence from randomized trials

Abstract

UN SDGs

Keywords

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