Potential histamine H2-receptor antagonists: diaminofurazan, a new 'urea equivalent' group (1,2)

G. Sorba; R. Calvino; A. Defilippi

Potential histamine H₂-receptor antagonists: diaminofurazan, a new 'urea equivalent' group (1,2)

G. Sorba, R. Calvino, A. Defilippi

Research output: Contribution to journal › Article › peer-review

Abstract

New histamine H₂-receptor antagonists related to cimetidine, ranitidine and lamtidine have been prepared and tested for their in vitro activity (guinea-pig isolated atrium). These substances contain as 'urea equivalent' group a diaminofurazan moiety. Ranitidine and lamtidine analogues display strong H₂-antagonist activity.

Original language	English
Pages (from-to)	571-574
Number of pages	4
Journal	European Journal of Medicinal Chemistry
Volume	20
Issue number	6
Publication status	Published - 1985
Externally published	Yes

Cite this

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title = "Potential histamine H2-receptor antagonists: diaminofurazan, a new 'urea equivalent' group (1,2)",

abstract = "New histamine H2-receptor antagonists related to cimetidine, ranitidine and lamtidine have been prepared and tested for their in vitro activity (guinea-pig isolated atrium). These substances contain as 'urea equivalent' group a diaminofurazan moiety. Ranitidine and lamtidine analogues display strong H2-antagonist activity.",

author = "G. Sorba and R. Calvino and A. Defilippi",

year = "1985",

language = "English",

volume = "20",

pages = "571--574",

journal = "European Journal of Medicinal Chemistry",

issn = "0223-5234",

publisher = "Elsevier Masson s.r.l.",

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T1 - Potential histamine H2-receptor antagonists

T2 - diaminofurazan, a new 'urea equivalent' group (1,2)

AU - Sorba, G.

AU - Calvino, R.

AU - Defilippi, A.

PY - 1985

Y1 - 1985

N2 - New histamine H2-receptor antagonists related to cimetidine, ranitidine and lamtidine have been prepared and tested for their in vitro activity (guinea-pig isolated atrium). These substances contain as 'urea equivalent' group a diaminofurazan moiety. Ranitidine and lamtidine analogues display strong H2-antagonist activity.

AB - New histamine H2-receptor antagonists related to cimetidine, ranitidine and lamtidine have been prepared and tested for their in vitro activity (guinea-pig isolated atrium). These substances contain as 'urea equivalent' group a diaminofurazan moiety. Ranitidine and lamtidine analogues display strong H2-antagonist activity.

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M3 - Article

SN - 0223-5234

VL - 20

SP - 571

EP - 574

JO - European Journal of Medicinal Chemistry

JF - European Journal of Medicinal Chemistry

IS - 6

ER -

Potential histamine H₂-receptor antagonists: diaminofurazan, a new 'urea equivalent' group (1,2)

Abstract

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