Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Gabriele A. Rolla; Mauro Botta; Lorenzo Tei; Claudia Cabella; Simona Ghiani; Chiara Brioschi; Alessandro Maiocchi

doi:10.1002/chem.201301837

Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Gabriele A. Rolla
, Mauro Botta
, Lorenzo Tei
, Claudia Cabella
, Simona Ghiani
, Chiara Brioschi
, Alessandro Maiocchi

Department of Science and Technological Innovation

Research output: Contribution to journal › Article › peer-review

Abstract

Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading Gd^III complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

Original language	English
Pages (from-to)	11189-11193
Number of pages	5
Journal	Chemistry - A European Journal
Volume	19
Issue number	34
DOIs	https://doi.org/10.1002/chem.201301837
Publication status	Published - 19 Aug 2013

Keywords

contrast agents
lanthanides
lipidic nanoparticles
magnetic resonance imaging
relaxivity

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10.1002/chem.201301837

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title = "Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes",

abstract = "Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.",

keywords = "contrast agents, lanthanides, lipidic nanoparticles, magnetic resonance imaging, relaxivity",

author = "Rolla, \{Gabriele A.\} and Mauro Botta and Lorenzo Tei and Claudia Cabella and Simona Ghiani and Chiara Brioschi and Alessandro Maiocchi",

year = "2013",

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AU - Rolla, Gabriele A.

AU - Botta, Mauro

AU - Tei, Lorenzo

AU - Cabella, Claudia

AU - Ghiani, Simona

AU - Brioschi, Chiara

AU - Maiocchi, Alessandro

PY - 2013/8/19

Y1 - 2013/8/19

N2 - Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

AB - Highly efficient magnetic resonance imaging (MRI) probes have been prepared by loading GdIII complexes on the surface of solid lipid nanoparticles (pSLNs). Applicability as molecular imaging probes is demonstrated by an in vitro model study with targeted pSLNs.

KW - contrast agents

KW - lanthanides

KW - lipidic nanoparticles

KW - magnetic resonance imaging

KW - relaxivity

UR - https://www.scopus.com/pages/publications/84882250985

U2 - 10.1002/chem.201301837

DO - 10.1002/chem.201301837

M3 - Article

SN - 0947-6539

VL - 19

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EP - 11193

JO - Chemistry - A European Journal

JF - Chemistry - A European Journal

IS - 34

ER -

Paramagnetic solid lipid nanoparticles as a novel platform for the development of molecular MRI probes

Abstract

Keywords

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