Paramagnetic GdIIIFeIII heterobimetallic complexes of DTPA-bis-salicylamide

S. Aime; M. Botta; M. Fasano; E. Terreno

doi:10.1016/0584-8539(93)80039-D

Paramagnetic Gd^IIIFe^III heterobimetallic complexes of DTPA-bis-salicylamide

S. Aime
, M. Botta
, M. Fasano
, E. Terreno

Research output: Contribution to journal › Article › peer-review

Abstract

The reaction between DTPA (diethylenetriaminepenta-acetic acid)-anhydride and p-aminosalicylic acid (PAS) affords a novel ligand, [DTPA(PAS)₂], able to form stable heterobimetallic complexes with Gd³⁺ and Fe³⁺ ions. The lanthanide ion occupies an internal coordination cage formed by three nitrogen atoms, two carboxylate and two carboxoamido groups of the ligand, whereas the outer salicylic moieties form stable chelate rings with Fe^III ions. The stoichiometry of the resulting heterobimetallic complexes, established by measurements of water proton relaxation enhancement, is [(H₂O)-Gd-DTPA(PAS)₂]₂-Fe(H₂O)₂ or [(H₂O)-Gd-DTPA(PAS)₂]₃-Fe depending on the pH of the aqueous solution. The individual contributions to the observed relaxation enhancement from Gd³⁺ and Fe³⁺ paramagnetic ions have been clearly distinguished and analysed.

Original language	English
Pages (from-to)	1315-1322
Number of pages	8
Journal	Spectrochimica Acta - Part A Molecular Spectroscopy
Volume	49
Issue number	9
DOIs	https://doi.org/10.1016/0584-8539(93)80039-D
Publication status	Published - Aug 1993
Externally published	Yes

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@article{e2c6e8bb8f65442da2c212cd70aad5b3,

title = "Paramagnetic GdIIIFeIII heterobimetallic complexes of DTPA-bis-salicylamide",

abstract = "The reaction between DTPA (diethylenetriaminepenta-acetic acid)-anhydride and p-aminosalicylic acid (PAS) affords a novel ligand, [DTPA(PAS)2], able to form stable heterobimetallic complexes with Gd3+ and Fe3+ ions. The lanthanide ion occupies an internal coordination cage formed by three nitrogen atoms, two carboxylate and two carboxoamido groups of the ligand, whereas the outer salicylic moieties form stable chelate rings with FeIII ions. The stoichiometry of the resulting heterobimetallic complexes, established by measurements of water proton relaxation enhancement, is [(H2O)-Gd-DTPA(PAS)2]2-Fe(H2O)2 or [(H2O)-Gd-DTPA(PAS)2]3-Fe depending on the pH of the aqueous solution. The individual contributions to the observed relaxation enhancement from Gd3+ and Fe3+ paramagnetic ions have been clearly distinguished and analysed.",

author = "S. Aime and M. Botta and M. Fasano and E. Terreno",

year = "1993",

month = aug,

doi = "10.1016/0584-8539(93)80039-D",

language = "English",

volume = "49",

pages = "1315--1322",

journal = "Spectrochimica Acta - Part A Molecular Spectroscopy",

issn = "0584-8539",

publisher = "Pergamon Press Ltd.",

number = "9",

}

TY - JOUR

T1 - Paramagnetic GdIIIFeIII heterobimetallic complexes of DTPA-bis-salicylamide

AU - Aime, S.

AU - Botta, M.

AU - Fasano, M.

AU - Terreno, E.

PY - 1993/8

Y1 - 1993/8

N2 - The reaction between DTPA (diethylenetriaminepenta-acetic acid)-anhydride and p-aminosalicylic acid (PAS) affords a novel ligand, [DTPA(PAS)2], able to form stable heterobimetallic complexes with Gd3+ and Fe3+ ions. The lanthanide ion occupies an internal coordination cage formed by three nitrogen atoms, two carboxylate and two carboxoamido groups of the ligand, whereas the outer salicylic moieties form stable chelate rings with FeIII ions. The stoichiometry of the resulting heterobimetallic complexes, established by measurements of water proton relaxation enhancement, is [(H2O)-Gd-DTPA(PAS)2]2-Fe(H2O)2 or [(H2O)-Gd-DTPA(PAS)2]3-Fe depending on the pH of the aqueous solution. The individual contributions to the observed relaxation enhancement from Gd3+ and Fe3+ paramagnetic ions have been clearly distinguished and analysed.

AB - The reaction between DTPA (diethylenetriaminepenta-acetic acid)-anhydride and p-aminosalicylic acid (PAS) affords a novel ligand, [DTPA(PAS)2], able to form stable heterobimetallic complexes with Gd3+ and Fe3+ ions. The lanthanide ion occupies an internal coordination cage formed by three nitrogen atoms, two carboxylate and two carboxoamido groups of the ligand, whereas the outer salicylic moieties form stable chelate rings with FeIII ions. The stoichiometry of the resulting heterobimetallic complexes, established by measurements of water proton relaxation enhancement, is [(H2O)-Gd-DTPA(PAS)2]2-Fe(H2O)2 or [(H2O)-Gd-DTPA(PAS)2]3-Fe depending on the pH of the aqueous solution. The individual contributions to the observed relaxation enhancement from Gd3+ and Fe3+ paramagnetic ions have been clearly distinguished and analysed.

UR - https://www.scopus.com/pages/publications/0343822789

U2 - 10.1016/0584-8539(93)80039-D

DO - 10.1016/0584-8539(93)80039-D

M3 - Article

SN - 0584-8539

VL - 49

SP - 1315

EP - 1322

JO - Spectrochimica Acta - Part A Molecular Spectroscopy

JF - Spectrochimica Acta - Part A Molecular Spectroscopy

IS - 9

ER -

Paramagnetic Gd^IIIFe^III heterobimetallic complexes of DTPA-bis-salicylamide

Abstract

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