Paramagnetic Complexes as Novel NMR pH Indicators

S. AIME; Mauro BOTTA; L. MILONE; E. TERRENO

Paramagnetic Complexes as Novel NMR pH Indicators

S. AIME
, Mauro BOTTA
, L. MILONE
, E. TERRENO

Department of Science and Technological Innovation

Research output: Contribution to journal › Article

Abstract

The remarkable pH dependence of the chemical shift separation (7.0 ± 0.1 ppm/pH unit) observed between the outer ¹H NMR resonances on the spectrum of the paramagnetic complex [Yb(dotp)]^5- [H₈dotp = 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetrakis- (methylenephosphonic acid)] in the pH range 5.0-7.5 at 39°C enables this compound to be considered as a potential NMR probe for in vivo pH measurements.

Original language	English
Pages (from-to)	1265-1266
Number of pages	2
Journal	Chemical Communications
Publication status	Published - 1996

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@article{f06c25367dd34540ab447da3a698239c,

title = "Paramagnetic Complexes as Novel NMR pH Indicators",

abstract = "The remarkable pH dependence of the chemical shift separation (7.0 ± 0.1 ppm/pH unit) observed between the outer 1H NMR resonances on the spectrum of the paramagnetic complex [Yb(dotp)]5- [H8dotp = 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetrakis- (methylenephosphonic acid)] in the pH range 5.0-7.5 at 39°C enables this compound to be considered as a potential NMR probe for in vivo pH measurements.",

author = "S. AIME and Mauro BOTTA and L. MILONE and E. TERRENO",

year = "1996",

language = "English",

pages = "1265--1266",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

}

TY - JOUR

T1 - Paramagnetic Complexes as Novel NMR pH Indicators

AU - AIME, S.

AU - BOTTA, Mauro

AU - MILONE, L.

AU - TERRENO, E.

PY - 1996

Y1 - 1996

N2 - The remarkable pH dependence of the chemical shift separation (7.0 ± 0.1 ppm/pH unit) observed between the outer 1H NMR resonances on the spectrum of the paramagnetic complex [Yb(dotp)]5- [H8dotp = 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetrakis- (methylenephosphonic acid)] in the pH range 5.0-7.5 at 39°C enables this compound to be considered as a potential NMR probe for in vivo pH measurements.

AB - The remarkable pH dependence of the chemical shift separation (7.0 ± 0.1 ppm/pH unit) observed between the outer 1H NMR resonances on the spectrum of the paramagnetic complex [Yb(dotp)]5- [H8dotp = 1,4,7,10-tetraazacyclododecane-N,N′,N″,N‴-tetrakis- (methylenephosphonic acid)] in the pH range 5.0-7.5 at 39°C enables this compound to be considered as a potential NMR probe for in vivo pH measurements.

UR - https://iris.uniupo.it/handle/11579/3656

M3 - Article

SN - 1359-7345

SP - 1265

EP - 1266

JO - Chemical Communications

JF - Chemical Communications

ER -

Paramagnetic Complexes as Novel NMR pH Indicators

Abstract

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