On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria

Gregory A. Moore; Sarah A. Jewell; Giorgio Bellomo; Sten Orrenius

doi:10.1016/0014-5793(83)80626-7

On the relationship between Ca²⁺ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria

Gregory A. Moore
, Sarah A. Jewell
, Giorgio Bellomo
, Sten Orrenius

Research output: Contribution to journal › Article › peer-review

Abstract

The release of Ca²⁺ from rat liver mitochondria induced by t-butylhydroperoxide metabolism is caused by pyridine nucleotide oxidation and precedes alterations in membrane permeability which appear to result from, rather than cause, Ca²⁺ release.

Original language	English
Pages (from-to)	289-292
Number of pages	4
Journal	FEBS Letters
Volume	153
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(83)80626-7
Publication status	Published - 21 Mar 1983
Externally published	Yes

Keywords

Calcium efflux
Mitochondria
Ruthenium red
Swelling
t-Butylhydroperoxide

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10.1016/0014-5793(83)80626-7

Cite this

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title = "On the relationship between Ca2+ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria",

abstract = "The release of Ca2+ from rat liver mitochondria induced by t-butylhydroperoxide metabolism is caused by pyridine nucleotide oxidation and precedes alterations in membrane permeability which appear to result from, rather than cause, Ca2+ release.",

keywords = "Calcium efflux, Mitochondria, Ruthenium red, Swelling, t-Butylhydroperoxide",

author = "Moore, \{Gregory A.\} and Jewell, \{Sarah A.\} and Giorgio Bellomo and Sten Orrenius",

note = "Funding Information: This work was supportedb y a grant from the Swedish Medical Research Council (proj. no. 03X-2471).",

year = "1983",

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doi = "10.1016/0014-5793(83)80626-7",

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AU - Moore, Gregory A.

AU - Jewell, Sarah A.

AU - Bellomo, Giorgio

AU - Orrenius, Sten

N1 - Funding Information: This work was supportedb y a grant from the Swedish Medical Research Council (proj. no. 03X-2471).

PY - 1983/3/21

Y1 - 1983/3/21

N2 - The release of Ca2+ from rat liver mitochondria induced by t-butylhydroperoxide metabolism is caused by pyridine nucleotide oxidation and precedes alterations in membrane permeability which appear to result from, rather than cause, Ca2+ release.

AB - The release of Ca2+ from rat liver mitochondria induced by t-butylhydroperoxide metabolism is caused by pyridine nucleotide oxidation and precedes alterations in membrane permeability which appear to result from, rather than cause, Ca2+ release.

KW - Calcium efflux

KW - Mitochondria

KW - Ruthenium red

KW - Swelling

KW - t-Butylhydroperoxide

UR - https://www.scopus.com/pages/publications/0020535984

U2 - 10.1016/0014-5793(83)80626-7

DO - 10.1016/0014-5793(83)80626-7

M3 - Article

SN - 0014-5793

VL - 153

SP - 289

EP - 292

JO - FEBS Letters

JF - FEBS Letters

IS - 2

ER -

On the relationship between Ca²⁺ efflux and membrane damage during t-butylhydroperoxide metabolism by liver mitochondria

Abstract

Keywords

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