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On the mode of baker's yeast reduction of C-7 --- C-10 2-alken-4-olides

  • Giovanni Fronza
  • , Claudio Fuganti
  • , Piero Grasselli
  • , Andrea Mele
  • , Antonella Sarra
  • , Gianna Allegrone
  • , Massimo Barbeni

Research output: Contribution to journalArticlepeer-review

Abstract

Baker's yeast reduction of lactones 8, a-d proceeds under kinetic resolution to give (S) 11, a-d of low ee values, increasing with the length of the side chain, occurring the double bond saturation in anti fashion on the beta re face, as indicated by the obtainment from 4 and 6 of 5 and 7, respectively.

Original languageEnglish
Pages (from-to)6467-6470
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number40
DOIs
Publication statusPublished - 1 Oct 1993
Externally publishedYes

Keywords

  • 2-alken-4-olides
  • baker's yeast
  • reduction
  • stereochemistry

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