Abstract
Hit the mark: The development of a short synthesis of ingenol may mark the beginning of a new era of natural products synthesis, an era where structural complexity does not deter the development of processes amenable to scale up. This may foster the exploration of biologically relevant chemical space and pave the way to the development of commercial syntheses of natural products.
| Original language | English |
|---|---|
| Pages (from-to) | 927-929 |
| Number of pages | 3 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 53 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 20 Jan 2014 |
| Externally published | Yes |
Keywords
- drug discovery
- ingenol
- natural products
- terpenoids
- total synthesis
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