Abstract
The role of Vitamin D hormone in human health and disease is still debated. Recently, growing attention has been paid to its putative role in cardiovascular system homeostasis with several studies that suggested a correlation between low vitamin D levels and increased cardiovascular risk. Several mechanisms are involved in the development of cardiovascular diseases: systemic inflammation, endothelial dysfunction, arterial hypertension and insulin resistance. In the present paper, we have revised the current literature supporting a role for vitamin D in the development of these pathogenetic processes. Finally, we have evaluated the current evidence linking vitamin D to atherosclerosis and its natural consequence, cardiovascular diseases.
Original language | English |
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Pages (from-to) | 261-278 |
Number of pages | 18 |
Journal | Open Rheumatology Journal |
Volume | 12 |
DOIs | |
Publication status | Published - 2018 |
Keywords
- Atherosclerosis
- Cardiovascular diseases
- Cardiovascular risk
- Inflammation
- Insulin resistance
- Vitamin D