Abstract
In this thesis muscular modifications in chronic spinal cord injured patients have been
investigated. Using a translational approach, a mini-invasive muscular biopsy
technique in Spinal Cord Injured patients has been validated. Moreover, the possible
role of circulating levels of myostatin as a possible candidate biomarker for muscular
modifications in chronic SCI patients has been evaluated. Lastly, the molecular
modifications of PGE2 pathway on muscular specimens of chronic SCI patients has
been studied.
All material is original and based on direct Author ’s experience.
| Original language | English |
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| Publication status | Published - 2014 |
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