MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis

D. Vecchio; E. Virgilio; P. Naldi; C. Comi; R. Cantello

doi:10.1016/j.msard.2018.02.006

MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis

D. Vecchio
, E. Virgilio
, P. Naldi
, C. Comi
, R. Cantello

Department of Translational Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Introduction: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement. Case report: A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression. Conclusion: MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.

Original language	English
Pages (from-to)	9-10
Number of pages	2
Journal	Multiple Sclerosis and Related Disorders
Volume	21
DOIs	https://doi.org/10.1016/j.msard.2018.02.006
Publication status	Published - Apr 2018

Keywords

Autoimmune rhombencephalitis
Brainstem in NMOSD
MOG-IgG

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title = "MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis",

abstract = "Introduction: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement. Case report: A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression. Conclusion: MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.",

keywords = "Autoimmune rhombencephalitis, Brainstem in NMOSD, MOG-IgG",

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T2 - a case of post-partum severe rhombencephalitis and transverse myelitis

AU - Vecchio, D.

AU - Virgilio, E.

AU - Naldi, P.

AU - Comi, C.

AU - Cantello, R.

PY - 2018/4

Y1 - 2018/4

N2 - Introduction: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement. Case report: A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression. Conclusion: MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.

AB - Introduction: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) associated disorders present with a spectrum of clinical pictures including brainstem involvement. Case report: A patient with the sudden onset of a post-partum severe rhombencephalitis causing respiratory failure (12 years after a mild transverse myelitis). Despite the aggressive clinical course, she had an impressive recovery after plasmapheresis, and no further relapses on immunosuppression. Conclusion: MOG-IgG disorders could relapse several years after onset and involve brainstem. Good prognosis is possible after treatment.

KW - Autoimmune rhombencephalitis

KW - Brainstem in NMOSD

KW - MOG-IgG

UR - https://www.scopus.com/pages/publications/85041729089

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DO - 10.1016/j.msard.2018.02.006

M3 - Article

SN - 2211-0348

VL - 21

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JO - Multiple Sclerosis and Related Disorders

JF - Multiple Sclerosis and Related Disorders

ER -

MOG-antibody demyelinating diseases: a case of post-partum severe rhombencephalitis and transverse myelitis

Abstract

Keywords

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