Mechanisms by which exercise training benefits patients with heart failure

Ettore Crimi; Louis J. Ignarro; Francesco Cacciatore; Claudio Napoli

doi:10.1038/nrcardio.2009.8

Mechanisms by which exercise training benefits patients with heart failure

Ettore Crimi
, Louis J. Ignarro
, Francesco Cacciatore
, Claudio Napoli

Research output: Contribution to journal › Review article › peer-review

Abstract

Clinical consequences of heart failure are fatigue, dyspnea, and progressive impairment of exercise tolerance. Regular exercise training is associated with health-improving effects. In patients with stable heart failure, exercise training can relieve symptoms, improve exercise capacity and quality of life, as well as reduce hospitalization and, to some extent, risk of mortality. Progressive exercise training is associated with pulmonary, cardiovascular, and skeletal muscle metabolic adaptations that increase oxygen delivery and energy production. This Review focuses on current knowledge of mechanisms by which progressive and moderate exercise training can have sustained beneficial effects on patients with heart failure.

Original language	English
Pages (from-to)	292-300
Number of pages	9
Journal	Nature Reviews Cardiology
Volume	6
Issue number	4
DOIs	https://doi.org/10.1038/nrcardio.2009.8
Publication status	Published - Apr 2009
Externally published	Yes

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10.1038/nrcardio.2009.8

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title = "Mechanisms by which exercise training benefits patients with heart failure",

abstract = "Clinical consequences of heart failure are fatigue, dyspnea, and progressive impairment of exercise tolerance. Regular exercise training is associated with health-improving effects. In patients with stable heart failure, exercise training can relieve symptoms, improve exercise capacity and quality of life, as well as reduce hospitalization and, to some extent, risk of mortality. Progressive exercise training is associated with pulmonary, cardiovascular, and skeletal muscle metabolic adaptations that increase oxygen delivery and energy production. This Review focuses on current knowledge of mechanisms by which progressive and moderate exercise training can have sustained beneficial effects on patients with heart failure.",

author = "Ettore Crimi and Ignarro, \{Louis J.\} and Francesco Cacciatore and Claudio Napoli",

note = "Funding Information: supported in part by a grant from the italian Ministery of University and research 2006 (PriN 2006, Principal investigator: Prof Napoli) and ricerca Finalizzata from italian Ministery of Health 2006 (Principal investigator: Dr Cacciatore).",

year = "2009",

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AU - Crimi, Ettore

AU - Ignarro, Louis J.

AU - Cacciatore, Francesco

AU - Napoli, Claudio

N1 - Funding Information: supported in part by a grant from the italian Ministery of University and research 2006 (PriN 2006, Principal investigator: Prof Napoli) and ricerca Finalizzata from italian Ministery of Health 2006 (Principal investigator: Dr Cacciatore).

PY - 2009/4

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N2 - Clinical consequences of heart failure are fatigue, dyspnea, and progressive impairment of exercise tolerance. Regular exercise training is associated with health-improving effects. In patients with stable heart failure, exercise training can relieve symptoms, improve exercise capacity and quality of life, as well as reduce hospitalization and, to some extent, risk of mortality. Progressive exercise training is associated with pulmonary, cardiovascular, and skeletal muscle metabolic adaptations that increase oxygen delivery and energy production. This Review focuses on current knowledge of mechanisms by which progressive and moderate exercise training can have sustained beneficial effects on patients with heart failure.

AB - Clinical consequences of heart failure are fatigue, dyspnea, and progressive impairment of exercise tolerance. Regular exercise training is associated with health-improving effects. In patients with stable heart failure, exercise training can relieve symptoms, improve exercise capacity and quality of life, as well as reduce hospitalization and, to some extent, risk of mortality. Progressive exercise training is associated with pulmonary, cardiovascular, and skeletal muscle metabolic adaptations that increase oxygen delivery and energy production. This Review focuses on current knowledge of mechanisms by which progressive and moderate exercise training can have sustained beneficial effects on patients with heart failure.

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SP - 292

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JO - Nature Reviews Cardiology

JF - Nature Reviews Cardiology

IS - 4

ER -

Mechanisms by which exercise training benefits patients with heart failure

Abstract

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