Management of young women with early breast cancer

Francesca Poggio; Matteo Lambertini; Claudia Bighin; Benedetta Conte; Eva Blondeaux; Alessia D'Alonzo; Chiara Dellepiane; Francesco Boccardo; Lucia Del Mastro

doi:10.1136/esmoopen-2018-000458

Management of young women with early breast cancer

Francesca Poggio
, Matteo Lambertini
, Claudia Bighin
, Benedetta Conte
, Eva Blondeaux
, Alessia D'Alonzo
, Chiara Dellepiane
, Francesco Boccardo
, Lucia Del Mastro

Research output: Contribution to journal › Review article › peer-review

Abstract

Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.

Original language	English
Article number	e000458
Journal	ESMO Open
Volume	3
DOIs	https://doi.org/10.1136/esmoopen-2018-000458
Publication status	Published - 1 Nov 2018
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

adjuvant treatments
breast cancer
fertility
premenopausal
young women

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10.1136/esmoopen-2018-000458

Cite this

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title = "Management of young women with early breast cancer",

abstract = "Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.",

keywords = "adjuvant treatments, breast cancer, fertility, premenopausal, young women",

author = "Francesca Poggio and Matteo Lambertini and Claudia Bighin and Benedetta Conte and Eva Blondeaux and Alessia D'Alonzo and Chiara Dellepiane and Francesco Boccardo and \{Del Mastro\}, Lucia",

note = "Publisher Copyright: {\textcopyright} 2019 Author(s) (or their employer(s). Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.",

year = "2018",

month = nov,

day = "1",

doi = "10.1136/esmoopen-2018-000458",

language = "English",

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journal = "ESMO Open",

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TY - JOUR

T1 - Management of young women with early breast cancer

AU - Poggio, Francesca

AU - Lambertini, Matteo

AU - Bighin, Claudia

AU - Conte, Benedetta

AU - Blondeaux, Eva

AU - D'Alonzo, Alessia

AU - Dellepiane, Chiara

AU - Boccardo, Francesco

AU - Del Mastro, Lucia

PY - 2018/11/1

Y1 - 2018/11/1

N2 - Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.

AB - Breast cancer is still the most frequent cancer diagnosed in women aged ≤40 years and the primary cause of death in this age group. The management of these patients needs a dedicated approach involving a multidisciplinary team that takes into account their treatment and survivorship issues. The present review aims to provide a perspective on the many challenges associated with treatment of young women with early breast cancer. We will focus on the standard (neo)adjuvant treatment, highlighting the paucity of age-specific results about the available genomic signatures, the groundbreaking landscape of adjuvant endocrine therapy and the relevant issue of the fertility preservation.

KW - adjuvant treatments

KW - breast cancer

KW - fertility

KW - premenopausal

KW - young women

UR - https://www.scopus.com/pages/publications/85060853207

U2 - 10.1136/esmoopen-2018-000458

DO - 10.1136/esmoopen-2018-000458

M3 - Review article

SN - 2059-7029

VL - 3

JO - ESMO Open

JF - ESMO Open

M1 - e000458

ER -

Management of young women with early breast cancer

Abstract

UN SDGs

Keywords

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