L'EMPLOI DE L'ANTICORPS MONOCLONAL KI-67 DANS L'ETUDE DE L'ACTIVITE PROLIFERATIVE DES TUMEURS UROLOGIQUES. DONNEES PRELIMINAIRES

Translated title of the contribution: Use of monoclonal antibodies KI-67 for assessment of proliferative activity of urologic tumors. Preliminary results

D. Fontana, M. Bellina, G. Valente, G. Fasolis, M. Colombo, M. Dublino, L. Rolle, F. Porpiglia

Research output: Contribution to journalArticlepeer-review

Abstract

The authors report the preliminary data of a study on the proliferative activity in urologic cancers. They use the monoclonal antibody KI-67 which can find out a nuclear antigen present only in cells in proliferative phase. They describe the methodology and report the results concerning 12 cancers of the kidney, 17 of the bladder, 17 of the prostate and 2 of the testicle. The most interesting results were obtained in the study of bladder cancer where they could pick out, in the context of the cancers with grading G2, a sub-group with proliferative characteristics similar to those of cancers G3 and vice-versa. They also obtained important results in the study of prostate cancer in hormonal therapy, as they could demonstrate the disappearance of the proliferative activity in patients responding clinically to the treatment.

Translated title of the contributionUse of monoclonal antibodies KI-67 for assessment of proliferative activity of urologic tumors. Preliminary results
Original languageFrench
Pages (from-to)549-552
Number of pages4
JournalJournal d'Urologie
Volume93
Issue number9-10
Publication statusPublished - 1987
Externally publishedYes

Fingerprint

Dive into the research topics of 'Use of monoclonal antibodies KI-67 for assessment of proliferative activity of urologic tumors. Preliminary results'. Together they form a unique fingerprint.

Cite this