Lanthanide(in) chelates for NMR biomedical applications

Silvio Aime; Mauro Botta; Mauro Fasano; Enzo Terreno

doi:10.1039/A827019Z

Lanthanide(in) chelates for NMR biomedical applications

Silvio Aime, Mauro Botta, Mauro Fasano, Enzo Terreno

Research output: Contribution to journal › Article › peer-review

Abstract

The peculiar magnetic properties of lanthanide(III) ions may be exploited for the development of powerful NMR probes for biomedical applications. Gd^III chelates are in current clinical use as contrast agents for magnetic resonance imaging. Other paramagnetic lanthanide(III) complexes endowed with shift reagent capabilities are used for the separation of NMR resonances of species present in the inner and outer cellular compartments and for the measurement of pH and temperature.

Original language	English
Pages (from-to)	19-29
Number of pages	11
Journal	Chemical Society Reviews
Volume	27
Issue number	1
DOIs	https://doi.org/10.1039/A827019Z
Publication status	Published - 1998
Externally published	Yes

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title = "Lanthanide(in) chelates for NMR biomedical applications",

abstract = "The peculiar magnetic properties of lanthanide(III) ions may be exploited for the development of powerful NMR probes for biomedical applications. GdIII chelates are in current clinical use as contrast agents for magnetic resonance imaging. Other paramagnetic lanthanide(III) complexes endowed with shift reagent capabilities are used for the separation of NMR resonances of species present in the inner and outer cellular compartments and for the measurement of pH and temperature.",

author = "Silvio Aime and Mauro Botta and Mauro Fasano and Enzo Terreno",

year = "1998",

doi = "10.1039/A827019Z",

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AU - Botta, Mauro

AU - Fasano, Mauro

AU - Terreno, Enzo

PY - 1998

Y1 - 1998

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AB - The peculiar magnetic properties of lanthanide(III) ions may be exploited for the development of powerful NMR probes for biomedical applications. GdIII chelates are in current clinical use as contrast agents for magnetic resonance imaging. Other paramagnetic lanthanide(III) complexes endowed with shift reagent capabilities are used for the separation of NMR resonances of species present in the inner and outer cellular compartments and for the measurement of pH and temperature.

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VL - 27

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JO - Chemical Society Reviews

JF - Chemical Society Reviews

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Lanthanide(in) chelates for NMR biomedical applications

Abstract

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