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L'amoxicillina nella tonsillectomia: Dati preliminari sulla valutazione delle concentrazioni sieriche e tessutali

Translated title of the contribution: Amoxicillin in tonsillectomy: Preliminary data on the evaluation of serum and tissue concentrations
  • Gianluca Averono
  • , Massimo Olina
  • , Matteo Basile
  • , Marco Bagnati
  • , Alessia Uglietti
  • , Pietro Luigi Garavelli
  • , Giorgio Bellomo
  • , Francesco Pia

Research output: Contribution to journalArticlepeer-review

Abstract

Amoxicillin was administered to 50 patients with chronic recurrent tonsillitis waiting for tonsillectomy. Group A (N=16) received 2.2 g of amoxicillin plus clavulanic acid with intravenous injection 10 minutes before tonsillectomy. Group B (N=34) was treated with 3 doses of amoxicillin-clavulanic acid administered orally the day before surgery, plus one oral administration 2 hours before tonsillectomy. Antibiotic doses were established on patient s weight using maximum suggested. The measures were estimated in serum and in tonsils using High Performance Liquid Chromatography, (HPLC). The data show better efficacy of intravenous administration than oral administration.

Translated title of the contributionAmoxicillin in tonsillectomy: Preliminary data on the evaluation of serum and tissue concentrations
Original languageItalian
Pages (from-to)314-315
Number of pages2
JournalRecenti Progressi in Medicina
Volume95
Issue number6
Publication statusPublished - Jun 2004
Externally publishedYes

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