Abstract
Amoxicillin was administered to 50 patients with chronic recurrent tonsillitis waiting for tonsillectomy. Group A (N=16) received 2.2 g of amoxicillin plus clavulanic acid with intravenous injection 10 minutes before tonsillectomy. Group B (N=34) was treated with 3 doses of amoxicillin-clavulanic acid administered orally the day before surgery, plus one oral administration 2 hours before tonsillectomy. Antibiotic doses were established on patient s weight using maximum suggested. The measures were estimated in serum and in tonsils using High Performance Liquid Chromatography, (HPLC). The data show better efficacy of intravenous administration than oral administration.
| Translated title of the contribution | Amoxicillin in tonsillectomy: Preliminary data on the evaluation of serum and tissue concentrations |
|---|---|
| Original language | Italian |
| Pages (from-to) | 314-315 |
| Number of pages | 2 |
| Journal | Recenti Progressi in Medicina |
| Volume | 95 |
| Issue number | 6 |
| Publication status | Published - Jun 2004 |
| Externally published | Yes |
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