Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

Tommaso Mauri; Eleonora Carlesso; Elena Spinelli; Cecilia Turrini; Francesca Dalla Corte; Riccarda Russo; Jean Damien Ricard; Antonio Pesenti; Oriol Roca; Giacomo Grasselli

doi:10.1016/j.jcrc.2019.06.020

Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

Tommaso Mauri
, Eleonora Carlesso
, Elena Spinelli
, Cecilia Turrini
, Francesca Dalla Corte
, Riccarda Russo
, Jean Damien Ricard
, Antonio Pesenti
, Oriol Roca
, Giacomo Grasselli

Research output: Contribution to journal › Article › peer-review

Abstract

The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.

Original language	English
Pages (from-to)	183-185
Number of pages	3
Journal	Journal of Critical Care
Volume	53
DOIs	https://doi.org/10.1016/j.jcrc.2019.06.020
Publication status	Published - Oct 2019
Externally published	Yes

Keywords

Acute hypoxemic respiratory failure
Electrical impedance tomography
Monitoring
Nasal high flow

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10.1016/j.jcrc.2019.06.020

Cite this

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title = "Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study",

abstract = "The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.",

keywords = "Acute hypoxemic respiratory failure, Electrical impedance tomography, Monitoring, Nasal high flow",

author = "Tommaso Mauri and Eleonora Carlesso and Elena Spinelli and Cecilia Turrini and Corte, \{Francesca Dalla\} and Riccarda Russo and Ricard, \{Jean Damien\} and Antonio Pesenti and Oriol Roca and Giacomo Grasselli",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2019",

month = oct,

doi = "10.1016/j.jcrc.2019.06.020",

language = "English",

volume = "53",

pages = "183--185",

journal = "Journal of Critical Care",

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T1 - Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients

T2 - A physiologic study

AU - Mauri, Tommaso

AU - Carlesso, Eleonora

AU - Spinelli, Elena

AU - Turrini, Cecilia

AU - Corte, Francesca Dalla

AU - Russo, Riccarda

AU - Ricard, Jean Damien

AU - Pesenti, Antonio

AU - Roca, Oriol

AU - Grasselli, Giacomo

PY - 2019/10

Y1 - 2019/10

N2 - The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.

AB - The ROX (Respiratory rate-OXygenation) index is an early predictor of failure of nasal high flow (NHF), with lower values indicating higher risk of intubation. We measured the ROX index at set flow rate of 30 and 60 l/min in 57 hypoxemic patients on NHF. Patients with increased ROX index values at higher flow (n = 40) showed worse baseline oxygenation, higher respiratory rate and lower ROX index in comparison to patients with unchanged or decreased ROX index values (n = 17). The ROX index variation between flows was correlated with the change in end expiratory lung volume. Set flow rate during NHF might impact the ROX index value.

KW - Acute hypoxemic respiratory failure

KW - Electrical impedance tomography

KW - Monitoring

KW - Nasal high flow

UR - https://www.scopus.com/pages/publications/85067898877

U2 - 10.1016/j.jcrc.2019.06.020

DO - 10.1016/j.jcrc.2019.06.020

M3 - Article

SN - 0883-9441

VL - 53

SP - 183

EP - 185

JO - Journal of Critical Care

JF - Journal of Critical Care

ER -

Increasing support by nasal high flow acutely modifies the ROX index in hypoxemic patients: A physiologic study

Abstract

Keywords

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