In vitro metabolism study of 2-isopropyl-9H-thioxanthen-9-one (2-ITX) in rat and human: Evidence for the formation of an epoxide metabolite

SILVIO APRILE, Erika Del Grosso, Giorgio GROSA

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)212-225
Number of pages14
JournalXenobiotica
Volume41
Issue number3
DOIs
Publication statusPublished - 1 Jan 2011

Keywords

  • Animals
  • Biochemistry
  • Cytochrome P-450 Enzyme System
  • Environmental Pollutants
  • Epoxy Compounds
  • Health, Toxicology and Mutagenesis
  • Humans
  • LC/MS
  • Male
  • Microsomes, Liver
  • Pharmacology
  • Photochemical Processes
  • Rats
  • Thioxanthenes
  • Toxicology
  • UV-cured inks
  • food contaminant
  • human microsomes
  • rat microsomes
  • reactive metabolites

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