Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction

Keyphrases

• Antitubulin Agents 100%
• Multicomponent Reactions 100%
• Microtubule Dynamics 100%
• Disrupter 100%
• Aza-analogue 100%
• Cancer Cell Lines 50%
• Biological Targets 50%
• Tubulin Polymerization 50%
• Antitubulin 50%
• Anticancer Therapy 50%
• Oncologic 50%
• Microtubules 50%
• Acetyl 50%
• Pediatric Cancer 50%
• Adult Cancer 50%
• Polymerization Assays 50%
• G2-M Cell Cycle Arrest 50%
• Tubulin Acetylation 50%
• Tenuazonic Acid 50%

Immunology and Microbiology

• Dynamics 100%
• Microtubule 100%
• Cancer Cell Line 50%
• Cell Cycle Arrest 50%
• Acetylation 50%
• Microtubule Assembly 50%
• Cell Cycle Checkpoint 50%
• Vertebral Column 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Tubulin 100%
• Tenuazonic Acid 100%
• Malignant Neoplasm 50%
• Biological Target 50%