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High stereoselective synthesis of diethyl (2,3-isopropylidene-5-trityl-α-d-ribofuranosyl)-methanephosphonate, a precursor to the phosphono analog of α-d-ribose 1-phosphate

  • Francesco Nicotra
  • , Luigi Panza
  • , Fiamma Ronchetti
  • , Lucio Toma

Research output: Contribution to journalArticlepeer-review

Abstract

The reaction of 2,3-isopropylidene-5-trityl-d-ribofuranose with methylenetriphenyl-phosphorane and the subsequent mercuriocyclization, iodomercuriation and Arbuzov reaction, allow a highly stereoselective entry to the phosphono analog of α-d-ribose 1-phosphate.

Original languageEnglish
Pages (from-to)5937-5938
Number of pages2
JournalTetrahedron Letters
Volume25
Issue number51
DOIs
Publication statusPublished - 1984
Externally publishedYes

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