Glycoconjugates of gadolinium complexes for MRI applications

David A. Fulton; Elisa M. Elemento; Silvio Aime; Linda Chaabane; Mauro Botta; David Parker

doi:10.1039/b517997a

Glycoconjugates of gadolinium complexes for MRI applications

David A. Fulton, Elisa M. Elemento, Silvio Aime, Linda Chaabane, Mauro Botta, David Parker

Department of Science and Technological Innovation

Research output: Contribution to journal › Article › peer-review

Abstract

Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

Original language	English
Pages (from-to)	1064-1066
Number of pages	3
Journal	Chemical Communications
Issue number	10
DOIs	https://doi.org/10.1039/b517997a
Publication status	Published - 2006

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10.1039/b517997a

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title = "Glycoconjugates of gadolinium complexes for MRI applications",

abstract = "Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.",

author = "Fulton, {David A.} and Elemento, {Elisa M.} and Silvio Aime and Linda Chaabane and Mauro Botta and David Parker",

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AU - Elemento, Elisa M.

AU - Aime, Silvio

AU - Chaabane, Linda

AU - Botta, Mauro

AU - Parker, David

PY - 2006

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AB - Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.

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U2 - 10.1039/b517997a

DO - 10.1039/b517997a

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SN - 1359-7345

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JO - Chemical Communications

JF - Chemical Communications

IS - 10

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Glycoconjugates of gadolinium complexes for MRI applications

Abstract

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