European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

M. N. Maisey; A. Lowry; A. Bischof-Delaloye; R. Fridrich; E. Inglese; M. N. Khalil; J. B. van der Schoot

doi:10.1007/BF01280254

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

M. N. Maisey
, A. Lowry
, A. Bischof-Delaloye
, R. Fridrich
, E. Inglese
, M. N. Khalil
, J. B. van der Schoot

Research output: Contribution to journal › Article › peer-review

Abstract

Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (^99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (²⁰¹T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for²⁰¹T1 and 96% for^99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study^99mTc-MIBI was as accurate as²⁰¹T1 for the detection of coronary artery stenoses.

Original language	English
Pages (from-to)	869-872
Number of pages	4
Journal	European Journal of Nuclear Medicine
Volume	16
Issue number	12
DOIs	https://doi.org/10.1007/BF01280254
Publication status	Published - Dec 1990
Externally published	Yes

Keywords

Coronary heart disease
Multi-centre comparison
Myocardial imaging
Technetium 99m methoxyisobutylisonitrile
Thallium 201

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10.1007/BF01280254

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@article{6fe1ebc016d74f49809fbdbbeec97128,

title = "European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease",

abstract = "Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81\% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80\% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98\% for201T1 and 96\% for99mTc-MIBI. Detection of CAD in total arteries was 68\% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.",

keywords = "Coronary heart disease, Multi-centre comparison, Myocardial imaging, Technetium 99m methoxyisobutylisonitrile, Thallium 201",

author = "Maisey, \{M. N.\} and A. Lowry and A. Bischof-Delaloye and R. Fridrich and E. Inglese and Khalil, \{M. N.\} and \{van der Schoot\}, \{J. B.\}",

year = "1990",

month = dec,

doi = "10.1007/BF01280254",

language = "English",

volume = "16",

pages = "869--872",

journal = "European Journal of Nuclear Medicine",

issn = "0340-6997",

publisher = "Springer Verlag",

number = "12",

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TY - JOUR

T1 - European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

AU - Maisey, M. N.

AU - Lowry, A.

AU - Bischof-Delaloye, A.

AU - Fridrich, R.

AU - Inglese, E.

AU - Khalil, M. N.

AU - van der Schoot, J. B.

PY - 1990/12

Y1 - 1990/12

N2 - Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.

AB - Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.

KW - Coronary heart disease

KW - Multi-centre comparison

KW - Myocardial imaging

KW - Technetium 99m methoxyisobutylisonitrile

KW - Thallium 201

UR - https://www.scopus.com/pages/publications/0025074203

U2 - 10.1007/BF01280254

DO - 10.1007/BF01280254

M3 - Article

SN - 0340-6997

VL - 16

SP - 869

EP - 872

JO - European Journal of Nuclear Medicine

JF - European Journal of Nuclear Medicine

IS - 12

ER -

European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

Abstract

Keywords

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