European multi-centre comparison of thallium 201 and technetium 99m methoxyisobutylisonitrile in ischaemic heart disease

M. N. Maisey, A. Lowry, A. Bischof-Delaloye, R. Fridrich, E. Inglese, M. N. Khalil, J. B. van der Schoot

Research output: Contribution to journalArticlepeer-review

Abstract

Fifty-six patients in Europe were entered into a multi-centre study to compare the accuracy of technetium 99m methoxyisobutylisonitrile (99mTc-MIBI) for the detection of coronary artery disease (CAD) with thallium 201 (201T1) chloride perfusion scanning. The results showed a high degree of concordance between the two radiopharmaceuticals. Some 81% (678/840) of myocardial segments showed the same result (normal, infarct or ischaemia), and 80% (45/56) of patients had the same diagnosis. Overall detection of CAD in patients was 98% for201T1 and 96% for99mTc-MIBI. Detection of CAD in total arteries was 68% for both agents. In this study99mTc-MIBI was as accurate as201T1 for the detection of coronary artery stenoses.

Original languageEnglish
Pages (from-to)869-872
Number of pages4
JournalEuropean Journal of Nuclear Medicine
Volume16
Issue number12
DOIs
Publication statusPublished - Dec 1990
Externally publishedYes

Keywords

  • Coronary heart disease
  • Multi-centre comparison
  • Myocardial imaging
  • Technetium 99m methoxyisobutylisonitrile
  • Thallium 201

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