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Erratum to: GLP-1: Benefits beyond pancreas

  • G. Muscogiuri
  • , A. Cignarelli
  • , F. Giorgino
  • , F. Prodam
  • , D. Santi
  • , G. Tirabassi
  • , G. Balercia
  • , R. Modica
  • , A. Faggiano
  • , A. Colao

Research output: Contribution to journalComment/debate

Abstract

Glucagon-like peptide 1 (GLP-1) is an intestinal hormone secreted after the ingestion of various nutrients. The main role of GLP-1 is to stimulate insulin secretion in a glucose-dependent manner. However, the expression of GLP-1 receptor was found to be expressed in a variety of tissues beyond pancreas such as lung, stomach, intestine, kidney, heart and brain. Beyond pancreas, a beneficial effect of GLP-1 on body weight reduction has been shown, suggesting its role for the treatment of obesity. In addition, GLP-1 has been demonstrated to reduce cardiovascular risk factors and to have a direct cardioprotective effect, fostering heart recovery after ischemic injury. Further, data from both experimental animal models and human studies have shown beneficial effect of GLP-1 on bone metabolism, either directly or indirectly on bone cells.
Original languageEnglish
Pages (from-to)115
Number of pages1
JournalJournal of Endocrinological Investigation
Volume38
Issue number1
DOIs
Publication statusPublished - 1 Jan 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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