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Enabling amidation in water: micellar catalysis approach for sustainable synthesis of iopamidol
Anita Zucchi
, Sara Mattiello
, Rachele Maschio
, Valentina Bellotti
,
Giovanni B. Giovenzana
, Luciano Lattuada
, Luca Beverina
Department of Pharmaceutical Sciences
Research output
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Contribution to journal
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Article
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peer-review
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Keyphrases
Iopamidol
100%
Amidation
100%
Sustainable Synthesis
100%
Micellar Catalysis
100%
Serinol
50%
Acyl
25%
Water-soluble
25%
Hydrolysis
25%
Surfactant
25%
Amines
25%
One-pot Reaction
25%
Triton X-100 (TX-100)
25%
Lipophilic
25%
Reaction Medium
25%
Acyl Chlorides
25%
Dichlorides
25%
Iodinated Contrast Agent
25%
Environmental Concern
25%
Aprotic
25%
Safety Concerns
25%
Organic Transformations
25%
Dimethylacetamide (DMAc)
25%
Regulatory Pressure
25%
Water Sensitivity
25%
Chemistry
Iopamidol
100%
Micellar Catalysis
100%
amidation
100%
Contrast Medium
25%
Water Soluble
25%
Surfactant
25%
Acyl Chloride
25%
Enzymatic Hydrolysis
25%
Triton X-100
25%
Organic Transformation
25%